A Study of Retreatment With Brentuximab Vedotin in Subjects With Classic Hodgkin Lymphoma or CD30-expressing Peripheral T Cell Lymphoma
NCT03947255 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2023-10-13
Summary
This study will look at whether brentuximab vedotin works and is safe in the re-treatment setting. To be in this study, patients must have already received brentuximab vedotin as treatment and have cancer that progressed (got worse) after stopping treatment.
Conditions
- Hodgkin Lymphoma
- Peripheral T Cell Lymphoma
- Anaplastic Large Cell Lymphoma
Interventions
- DRUG
-
brentuximab vedotin
1.8 mg/kg given intravenously (IV)
Sponsors & Collaborators
-
Seagen Inc.
lead INDUSTRY
Principal Investigators
-
Dominic Lai, MD · Seagen Inc.
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-28
- Primary Completion
- 2022-11-06
- Completion
- 2022-11-06
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Phase 1 Study of Brentuximab Vedotin Given Sequentially and Combined With Multi-Agent Chemotherapy for CD30-Positive Mature T-Cell and NK-Cell Neoplasms
NCT01309789 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Brentuximab Vedotin Combined With Nivolumab for Relapsed or Refractory Hodgkin Lymphoma
NCT02572167 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Brentuximab Vedotin and Pembrolizumab in Treating Patients With Recurrent Peripheral T-Cell Lymphoma
NCT04795869 ·Status: WITHDRAWN ·Phase: PHASE2
-
Study of Brentuximab Vedotin (SGN-35) in Pediatric Participants With Relapsed or Refractory (r/r) Systemic Anaplastic Large-Cell Lymphoma or Hodgkin Lymphoma
NCT01492088 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Brentuximab Vedotin Before Autologous Stem Cell Transplant in Treating Patients With Hodgkin Lymphoma
NCT01393717 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL)
NCT02588651 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I-II Study in CD30 Positive Diffuse Large B-cell Lymphoma Patients Refractory to First Line Chemotherapy or in First Relapse
NCT03356054 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of Brentuximab Vedotin in Participants With Relapsed or Refractory Hodgkin Lymphoma
NCT01990534 ·Status: COMPLETED ·Phase: PHASE4
-
Brentuximab Vedotin and Lenalidomide in Treating Patients With Relapsed or Refractory T-Cell Lymphomas
NCT03373305 ·Status: WITHDRAWN ·Phase: PHASE1
-
Pembrolizumab and Brentuximab Vedotin in Subjects With Relapsed/Refractory T-cell Lymphoma
NCT05313243 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line Treatment
NCT02927769 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Brentuximab Vedotin Combined With Bendamustine in Patients With Hodgkin Lymphoma
NCT01874054 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma
NCT00848926 ·Status: COMPLETED ·Phase: PHASE2
-
Patient-reported and Clinical Outcomes in Adults With Relapsed or Refractory Hodgkin's Lymphoma Receiving Brentuximab Vedotin
NCT03440788 ·Status: UNKNOWN
-
A Phase 1 Study in Patients With Relapsed or Refractory Hodgkin Lymphoma or Systemic Anaplastic Large Cell Lymphoma
NCT01950364 ·Status: COMPLETED ·Phase: PHASE1
-
Brentuximab Vedotin Plus DHAP in Relapsed or Refractory Hodgkin's Lymphoma
NCT05243693 ·Status: RECRUITING ·Phase: PHASE2
-
Brentuximab Vedotin, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
NCT02227199 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Brentuximab Vedotin in Refractory/Relapsed Hodgkin Lymphoma Treated by ICE
NCT02686346 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Nivolumab Plus Brentuximab Vedotin Versus Brentuximab Vedotin Alone in Patients With Advanced Stage Classical Hodgkin Lymphoma, Who Are Relapsed/ Refractory or Who Are Not Eligible for Autologous Stem Cell Transplant,
NCT03138499 ·Status: TERMINATED ·Phase: PHASE3
-
Brentuximab Vedotin Associated With Chemotherapy in Untreated Patients With Hodgkin Lymphoma.
NCT02292979 ·Status: COMPLETED ·Phase: PHASE2
-
Brentuximab Vedotin in the Elderly Hodgkin Lymphoma Patients at First Relapse or With Primary Refractory Disease.
NCT02227433 ·Status: COMPLETED ·Phase: PHASE2
-
Brentuximab Vedotin With or Without Nivolumab in Treating Patients With Relapsed or Refractory CD30+ Lymphoma
NCT01703949 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma
NCT04561206 ·Status: RECRUITING ·Phase: PHASE2
-
A Treatment-Option Protocol to Provide Brentuximab Vedotin to Eligible Patients Completing Studies SGN35-005 or C25001
NCT01196208 ·Status: NO_LONGER_AVAILABLE
-
Brentuximab Vedotin in Chinese Participants With Relapsed/Refractory CD30-Positive Hodgkin Lymphoma (HL) or Systemic Anaplastic Large Cell Lymphoma (sALCL)
NCT02939014 ·Status: COMPLETED ·Phase: PHASE2