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Sensory Afferents for Deep Pressure Sensation

NCT03937778 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 7

Last updated 2021-10-05

Study results available
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Summary

Background:

Much is known about how people perceive light touch, temperature, and pain. But less is known about how deep pressure is perceived. Deep pressure is an important part of many touch therapies, like massage therapy. Researchers want to learn more to help people with chronic pain and other disorders.

Objective:

To find out which sensory nerve fibers are involved in feeling the sensation of deep pressure.

Eligibility:

Healthy people ages 18 50 enrolled in study number 16-AT-0077

Design:

Participants will be screened under study number 16-AT-0077

Participants will have 1 visit that lasts about 2 hours.

Participants will have a brief medical interview. They will have a urine test.

Participants will have ischemic nerve block on 1 arm. A blood pressure cuff will be inflated until the arm is numb for up to an hour.

Participants will have tests to see how they perceive different sensations. They will rate gentle brushing on the hands and forearms. They will rate gentle pressure squeezing from a hand massager on the hands and forearms.

Participants will receive other sensations such as vibration, cool, warm, pinprick without piercing the skin, finger movement, and pressure. They will be asked to rate or respond to the sensations. They will be asked to rate any pain or discomfort from the nerve block on an ongoing basis.

Conditions

  • Normal Physiology

Interventions

BEHAVIORAL

Deep pressure block

Apply deep pressure block by using blood pressure cuff.

Sponsors & Collaborators

  • National Center for Complementary and Integrative Health (NCCIH)

    lead NIH

Principal Investigators

  • Alexander T Chesler, Ph.D. · National Center for Complementary and Integrative Health (NCCIH)

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-20
Primary Completion
2020-11-17
Completion
2020-11-17

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03937778 on ClinicalTrials.gov