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Detection of Bacterial DNA and Collagen Metabolism in Acutely Ruptured Achilles Tendons

NCT03931486 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2021-07-29

No results posted yet for this study

Summary

The etiology and pathogenesis of acute Achilles tendon ruptures are complex and not fully understood. It is well known that they are associated with pre-existing pathological alterations, similar to the changes observed in tendinopathy.

The present study investigates if bacteria and collagen metabolism play a role in the etiology of acute Achilles tendon rupture. During surgery, 20 patients will have taken two biopsies from the ruptured part of the tendon and two biopsies from the healthy tissue of the same tendon 2-4 cm proximal to the rupture, as a control.

Conditions

  • Achilles Tendon Rupture

Sponsors & Collaborators

  • Bispebjerg Hospital

    collaborator OTHER

  • Copenhagen University Hospital, Hvidovre

    lead OTHER

Principal Investigators

  • Kristoffer W Barfod, MD · Copenhagen University Hospital, Hvidovre

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-05-03
Primary Completion
2021-04-01
Completion
2021-04-01

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03931486 on ClinicalTrials.gov