Achilles Tendinopathy Treated With Training and Injections

Summary

The purpose of this study is to compare in a randomized double blinded controlled trial the effect of heavy slow resistance exercises combined with ultrasound guided injections with local anesthetic with or without glucocorticosteroid in patients with achilles tendinopathy.

Conditions

• Achilles Tendinopathy

Interventions

BEHAVIORAL

Reduction in running and jumping

Advocate to avoid running and jumping sports for the first 3 months, thereafter slowly progressing to normal sport activity.

OTHER

Training

Patients are instructed to carry out strengthening exercises for the diseased achilles tendon 3 times a week. Physiotherapist will instruct all patients in these heavy slow resistance exercises. First time one week after the first injection, and then week 3, 6, 10. The patient will register all training on a diary and on an App.

DRUG

Ultrasound guided injection with Glucocorticosteroid

Ultrasound guided injection in Kagers triangle underneath the thickest part of the achilles tendon with 1ml Lidocain 5 mg/ml and 1 ml methylprednisolone 40mg/ml. Injection is given every months until the tendon pain is markedly reduced (VAS morning pain: 0-20, and VAS training pain: 0-40, and Global recovery rating scale (-5 to +5) is +3 to +5 ). (max 3 injections).

DRUG

Ultrasound guided injection with local anaestethic

Ultrasound guided injection in Kagers triangle underneath the thickest part of the achilles tendon with 1ml Lidocain 5 mg/ml and 1 ml of intralipid (for blinding). Injection is given every months until the tendon pain is markedly reduced (VAS morning pain: 0-20, and VAS training pain: 0-40, and Global recovery rating scale (-5 to +5) is +3 to +5 ). (max 3 injections).

Sponsors & Collaborators

• The Danish Rheumatism Association

  collaborator OTHER

• Bispebjerg Hospital

  lead OTHER

Principal Investigators

• Finn E Johannsen, MD · Institute of Sports Medicine Copenhagen, University of Copenhagen, Denmark

• Jens L Olesen, MD, PhD · Institute of Sports Medicine Copenhagen, University of Copenhagen, Denmark

• Michael S Rathleff, PT, PhD · Research Unit for General Practice in Aalborg, Denmark

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-04-30

Primary Completion

2020-12-20

Completion

2020-12-20

Countries

• Denmark

Study Locations