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The Effect of Hyperoxia on Cardiac Output

NCT03930979 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2020-06-26

No results posted yet for this study

Summary

Rational: Preoxygenation is a standard procedure before (deep) sedation in the ED. However, there is literature suggesting that too much oxygen can be harmful. One potential detrimental effect is a decrease in cardiac output due to coronary vasoconstriction. So far, it is unknown if this effect is rate dependent and if it also occurs after only a short period of hyperoxia, as patients experience during procedural sedation pre-oxygenation.

Objective: To investigate if hyperoxia has a negative effect on Cardiac index (CI) in patients undergoing procedural sedation in the ED.

Conditions

  • Hyperoxia
  • Cardiac Output, Low

Sponsors & Collaborators

  • Frisius Medisch Centrum

    lead OTHER

Principal Investigators

  • Ewoud ter Avest, MD, PhD · medical center leeuwarden

  • Renate Stolmeijer, MD · medical center leeuwarden

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-05-01
Primary Completion
2019-06-07
Completion
2019-06-07

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03930979 on ClinicalTrials.gov