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Ventricular Stimulation as Predictor of Hypovolemia After Cardiac Surgery

NCT03926910 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2021-11-29

No results posted yet for this study

Summary

The purpose of the study is to validate a ventricular pacing test as a predictor of preload dependency in post cardiac surgery patients.

Conditions

  • Cardiac Surgery
  • Hypovolemia

Interventions

DIAGNOSTIC_TEST

Detection of hypovolemia using a ventricular stimulation without atrial pacing

Upon the return in intensive care: * Baseline measurements: 1) Three measurements of blood pressure during inspiration and 3 during expiration will be collected for averaging systolic blood pressure, diastolic blood pressure, mean arterial pressure and ΔPP. Data from a pulmonary artery catheter will be also collected. * Realization of VESAP pacing with adjustment of the pacemaker (PM) at a heart rate 5 bpm higher than the heart rate of the patient. After 20 seconds of stimulation, recording of the blood pressure curve as done at baseline during at least 3 respiratory cycles, * Then vascular filling with 500 ml of physiologic saline solution over 10 minutes and new set of measurement (same than at baseline) * Second realization of VESAP pacing, and new set of measurement (same than at Baseline) * Then, if the ΔPP is \>10%, new vascular filling with 500 ml of physiologic saline solution over 10 min and new set of measurements as previously performed.

Sponsors & Collaborators

  • CMC Ambroise Paré

    lead OTHER

Principal Investigators

  • Philippe ESTAGNASIÉ, MD · CMC Ambroise Paré

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-07-22
Primary Completion
2020-10-13
Completion
2020-10-14

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03926910 on ClinicalTrials.gov