Neuropeptides and Venous Pelvic Pain
NCT03921788 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2023-10-23
Summary
Mechanisms of the development of pain in chronic venous diseases (CVD), including pelvic congestion syndrome (PCS), are studied incompletely. The existing hypotheses of the occurrence of venous pelvic pain (VVP) do not allow to answer the question why some patients have no pain syndrome while others have very pronounced pain despite the same morphofunctional changes in the pelvic veins? The investigators are planning to carry out a study aimed at studying the content of calcitonin gene-related peptide (CGRP) and substance P (SP) in the serum of patients with pelvic veins and pelvic pain, and to study the relationship between the values of CGRP and SP in these patients.
Conditions
- Pelvic Pain
- Varicose Veins Pelvic
- Pelvic Congestion Syndrome
Sponsors & Collaborators
-
Pirogov Russian National Research Medical University
lead OTHER
Principal Investigators
-
Natalia V Koroleva, PhD · Pirogov Russian National Research Medical University
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-04-01
- Primary Completion
- 2021-12-12
- Completion
- 2022-02-11
Countries
- Russia
Study Locations
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