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The Role of Pyroptosis in Chronic Venous Disease

NCT03744858 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2018-11-16

No results posted yet for this study

Summary

Enrollment criteria and clinical data collection: following the principles of medical ethics, the development of inclusion and exclusion criteria. Selecting 200 cases of chronic venous disease (CVD) according to the Comprehensive Classification System for Chronic Venous Disorders (CEAP) divided into 6 Clinical stages (C1-C6) (Group A). Selecting 200 healthy participants without CVD (C0) as controls (Group B). Blood samples will be collected from both groups. Markers of pyroptosis (NETs, Caspase-1 and Cytokines) will be evaluated between the two groups and between the subgroups, according to clinical stage, in group A.

Conditions

  • Inflammation
  • Veins
  • Complication
  • Varicose Veins
  • Varicose Ulcer

Interventions

PROCEDURE

Peripheral blood draw

Peripheral vein blood draw will be performed to all participants in order to collect blood samples to be evaluated.

Sponsors & Collaborators

  • University of Catanzaro

    lead OTHER

Principal Investigators

  • Raffaele Serra, MD, PhD · University Magna Graecia of Catanzaro

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-12
Primary Completion
2019-11-12
Completion
2020-11-12

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03744858 on ClinicalTrials.gov