Integrated Approaches for Identifying Molecular Targets in Liver Disease
NCT03915002 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 155
Last updated 2023-11-07
Summary
To provide a framework for successful clinical trials testing novel targets for therapy in liver disease.
To identify molecular and cellular drivers of liver disease to provide a molecular classification and study the determinants or key drivers of disease progression.
Consecutive patients admitted with steatohepatitis (alcoholic or non-alcoholic) will be enrolled in this study where liver tissue, blood and stool will be collected to discover and validate factors associated with diagnosis, severity, histological characteristics, development of decompensations, progression of disease and survival.
Conditions
- Alcoholic Liver Disease
- Non-Alcoholic Fatty Liver Disease
- Steatohepatitis, Nonalcoholic
- Steatohepatitis
Sponsors & Collaborators
-
University of Pittsburgh
lead OTHER
Principal Investigators
-
Jaideep Behari, MD, PhD · Associate Professor
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-06-13
- Primary Completion
- 2023-04-12
- Completion
- 2023-04-12
Countries
- United States
Study Locations
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