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Imaging of Arthropathy in Boys With Hemophilia in China

NCT03914716 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 49

Last updated 2024-04-19

No results posted yet for this study

Summary

Hemophilia is a genetic condition characterized by marked phenotypic heterogeneity. Bleeding into a joint is the single most important risk factor for the development of hemophilic arthropathy (HA). It is thought that clinical and imaging manifestations of HA are at least partially attributable to genetic polymorphisms unrelated to the hemophilia genotype. Identifying and characterizing biologic factors that could explain differences in susceptibility to joint degeneration of patients with hemophilia would help stratify patients according to the risk of degeneration of their joints and develop personalized therapeutic and prophylactic strategies. This study is conducted in China.

Conditions

Interventions

DIAGNOSTIC_TEST

Study group

Subjects will have physical, imaging examinations and provide samples for biological markers

Sponsors & Collaborators

  • Beijing Children's Hospital, Baxalta US Inc.

    collaborator UNKNOWN

  • Andrea Doria

    lead OTHER

Principal Investigators

  • Andrea Doria, MD · The Hospital for Sick Children

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
4 Years
Max Age
11 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-21
Primary Completion
2022-02-02
Completion
2023-11-30

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03914716 on ClinicalTrials.gov