Quantitative GLP-1 Receptor Imaging Correlated to ex Vivo Distribution of In-111-exendin
NCT03889496 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2023-07-12
Summary
The main goal is to study the correlation of pancreatic uptake of In-111-DTPA-exendin-4 (measured by ex vivo counting) with the beta cell mass determined in the pancreatic specimens obtained after surgery.
Conditions
Interventions
- RADIATION
-
indium-111-exendin SPECT/CT
SPECT/CT imaging after injection with In-111-DTPA-exendin-4
Sponsors & Collaborators
-
Radboud University Medical Center
lead OTHER
Principal Investigators
-
Martin Gotthardt, Prof. Dr. · Radboud University Medical Center
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-11-16
- Primary Completion
- 2021-06-14
- Completion
- 2021-06-14
Countries
- Netherlands
Study Locations
More Related Trials
-
The Effect of the GLP-1 Analogue Exenatide on Type 2 Diabetes in CNS and Heart During Hyperglycemia Assessed by PET
NCT00747968 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A GLP-1 Receptor PET Imaging Substudy Within the VER-A-T1D Trial Investigating the Effects on Beta Cell Mass
NCT04615910 ·Status: RECRUITING ·Phase: PHASE2
-
68Ga-NODAGA-exendin-4 PET/CT for Diagnostic Imaging in AHH
NCT03189953 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effect of Liraglutide on Fatty Liver Content and Lipoprotein Metabolism
NCT02721888 ·Status: TERMINATED ·Phase: PHASE4
-
Cardiovascular Effects of GLP-1 Receptor Activation
NCT03101930 ·Status: COMPLETED ·Phase: PHASE4
-
GLP-1 Mediating DPP-4 Inhibition in Type 2 Diabetes
NCT02639130 ·Status: COMPLETED ·Phase: PHASE4
-
Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related Disease
NCT06725693 ·Status: RECRUITING
-
Regulation of Insulin Secretion by the GLP-1 Receptor
NCT02844907 ·Status: TERMINATED ·Phase: PHASE4
-
Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients
NCT02655770 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of GLP-1 on Postprandial Glucagon Secretion Independent of The Gastric Emptying Rate
NCT02584582 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Effect of Liraglutide on Vascular Inflammation in Type-2 Diabetes
NCT03449654 ·Status: COMPLETED ·Phase: PHASE4
-
11C-5-HTP PET in Clinical Islet Transplantation
NCT02689479 ·Status: COMPLETED ·Phase: NA
-
The Aim is to Estimate the Total Amount of Insulin-producing Cells in the Pancreas by MRI.
NCT00280085 ·Status: TERMINATED ·Phase: NA
-
GLP-1 Receptor Expression in CHI
NCT03768518 ·Status: UNKNOWN
-
A Dose-response Study Examining the Contribution of GLP-1 Receptor Signaling to Glucagon-stimulated Insulin Secretion
NCT04459338 ·Status: COMPLETED ·Phase: PHASE3
-
The Role of Endogenous Glucagon-like Peptide 1 (GLP-1) in Type 2 Diabetes Mellitus (T2DM)
NCT01449019 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Adiposity on Hepatic and Peripheral Insulin Resistance in Type 1 Diabetes
NCT03582956 ·Status: TERMINATED ·Phase: NA
-
Investigating the Effect of Liraglutide on the Endogenous Glucose Production During in Tye 1 Diabetes Subjects
NCT02408705 ·Status: COMPLETED ·Phase: PHASE2
-
Antigen-Lipid-Driven Monoclonal Gammopathies Targeting Epicardial Fat
NCT02920190 ·Status: WITHDRAWN ·Phase: PHASE4
-
Liraglutide Actions on the Liver: Effects on Glucose Phosphorylation
NCT02198209 ·Status: WITHDRAWN ·Phase: PHASE4
-
The Contribution of Incretin Hormones to Post-prandial Glucose Metabolism After Roux-en-Y Gastric Bypass
NCT01843881 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Anti-diabetic Effects of Liraglutide in Adolescents and Young Subjects With Type 1 Diabetes
NCT01722227 ·Status: WITHDRAWN ·Phase: PHASE3
-
Dynamics of Insulin Absorption in Subclinical Lipohypertrophy Using the Euglycemic Clamp Technique
NCT03229850 ·Status: WITHDRAWN ·Phase: NA
-
Effect of GLP-1 Receptor Agonists on Trabecular Bone Score
NCT04964388 ·Status: TERMINATED ·Phase: PHASE2
-
Raclopride-PET/MRT
NCT03637075 ·Status: COMPLETED ·Phase: NA