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Functional Roles of Dorsolateral Prefrontal Cortex

NCT03882931 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2019-11-19

No results posted yet for this study

Summary

Dorsolateral prefrontal cortex (DLPFC) has been found to be involved in cognitive functions such as executive function, response selection, and working memory. By applying transcranial magnetic stimulation (TMS) or transcranial focused ultrasound (FUS), which is a technology to temporally alter brain state in the stimulation site, the investigators aim to find supporting evidence for the causal relationship between the targeted stimulation site and motor learning improvement or response selection.

Conditions

  • Healthy Participants

Interventions

OTHER

Theta Burst Transcranial Magnetic Stimulation

Theta Bursts are short bursts of stimulation at high frequencies, which are applied 5 times per second

OTHER

Focused Ultrasound

Low intensity focused ultrasound is sound energy stimulation at a low intensity of 1-30 W/cm2

OTHER

Sham

The investigators will simulate theta bursts pulses similar to the Theta Burst Transcranial Magnetic Stimulation groups but without stimulation.

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Wynn Legon, PhD · University of Virginia

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-28
Primary Completion
2020-01-27
Completion
2020-01-27

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03882931 on ClinicalTrials.gov