MedTrace Logo

Lateral Ridge Augmentation Using Allograft Blocks and GBR for Implant Sites

NCT03879967 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2019-03-19

No results posted yet for this study

Summary

Clinicians are increasingly faced with the challenge of reconstructing the alveolar ridge as more patients desire fixed implant-supported restorations. Reconstruction of large horizontal alveolar defects still remains a challenge in implantology. Although autogenous blocks from intraoral sites are proven effective for such defects, donor site morbidity and limited graft availability are major limitations. Allogenic bone blocks have been proposed to overcome these limitations, however, the outcomes reported in the literature are inconclusive. In this case series, the efficacy of allogenic blocks for lateral augmentation of atrophic ridges was evaluated, over a three-year period.

In nineteen edentulous sites from ten patients, cortico-cancellous allogenic blocks (PHOENIX, TBF, France) were shaped to the defect and screw-fixated. A double-layer of autogenous chips and demineralized bovine bone (Bio-Oss, Geistlich Pharma AG, Switzerland) was used to fill the voids. The augmented site was covered by non-cross-linked collagen membrane (Bio-Gide, Geistlich Pharma AG, Switzerland). After a healing period of 9 months, implants were placed and CBCT analysis was performed post-implantation. Following a period of 34 months of function (range 22 to 44 months), patients were clinically and radiographically re-examined.

Conditions

  • Alveolar Ridge Augmentation

Interventions

DEVICE

Allograft block graft

The graft used is a mineralized, cortico-cancellous, delipidized, lyophilized allogenic block.

Sponsors & Collaborators

  • University of Bern

    lead OTHER

Principal Investigators

  • Daniel A Buser Prof, DDS,DMD · Department of Oral Surgery and Stomatology, ZMK, University of Bern

  • Vivianne Chappuis Prof, PD, DMD · Department of Oral Surgery and Stomatology, ZMK, University of Bern

  • Odette Engel, Dr med dent · Department of Oral Surgery and Stomatology, ZMK, University of Bern

  • Supriya Ebenezer, BDS, MDS · Department of Oral Surgery and Stomatology, ZMK, University of Bern

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-06-11
Primary Completion
2016-12-07
Completion
2018-05-14

Countries

  • Switzerland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03879967 on ClinicalTrials.gov