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Pilot Optimizing Transfusion Thresholds in Critically-ill Children With Anaemia

NCT03871244 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2021-09-28

No results posted yet for this study

Summary

The Pilot Optimizing Transfusion Thresholds in Critically-ill Children with Anaemia (P-OpTTICCA) study is a pilot trial for a large pragmatic international parallel open-label non-inferiority randomised controlled trial. The primary outcome of the pilot study is feasibility.

Conditions

Interventions

PROCEDURE

Less red blood cell transfusions

The instructions given to caregivers will be to consider prescribing a red blood cell transfusion only if the hemoglobin level is ≤ 70 g per L.

PROCEDURE

More red blood cell transfusion (standard transfusion strategy in PICU)

The instructions given to caregivers will be to prescribe a red blood cell transfusion according to their usual standard practice

Sponsors & Collaborators

  • Oxford University Hospitals NHS Trust

    collaborator OTHER

  • Hôpital Jeanne de Flandre

    collaborator UNKNOWN

  • NHS Blood and Transplant

    collaborator OTHER_GOV

  • St. Justine's Hospital

    lead OTHER

Principal Investigators

  • Jacques Lacroix · St-Justine Hospital Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
1 Day
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-03
Primary Completion
2021-12-31
Completion
2022-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03871244 on ClinicalTrials.gov