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Hepatitis B Virus Infection After Liver Transplantation in Children

NCT03865966 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2019-07-08

No results posted yet for this study

Summary

China is a highly prevalent area of hepatitis B virus（HBV） infection, with at least 75 million hepatitis B virus carriers, and 80% of primary hepatocellular carcinoma (HCC) is associated with chronic hepatitis B virus infection. Liver transplantation is currently the preferred method for end-stage liver disease such as biliary atresia and cirrhosis in children. In recent years, children's liver transplantation has developed rapidly and the number of developments has increased significantly. If there is chronic hepatitis B virus infection in the donor liver, it may cause HBV transmission, or the patient may have a low-load occult hepatitis B virus infection, and after immunosuppressive treatment, it may lead to hepatitis B virus infection after surgery.

Conditions

  • Hepatitis B Infection

Interventions

OTHER

No intervention

Sponsors & Collaborators

  • Qiu Li

    lead OTHER

Principal Investigators

  • Yao Zhao · Chongqing Children's Hospital of Chongqing Medical University

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-07-05
Primary Completion
2023-12-31
Completion
2025-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03865966 on ClinicalTrials.gov