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High-flow Nasal Cannula Flow Rates, Severe Bronchiolitis

NCT03859947 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 168

Last updated 2019-03-01

No results posted yet for this study

Summary

Objective: The investigators aimed to compare the heated humidified high-flow nasal cannula (HHHFNC) flow rate of 1-L/kg/min (1L) with 2-L/kg/min (2L) in patients with severe bronchiolitis presenting to the pediatric emergency department.

Study design: The investigators performed a study in which all patients were allocated to receive these two flow rates. The primary outcome was admitted as treatment failure, which was defined as a clinical escalation in respiratory status. Secondary outcomes covered a decrease of respiratory rate (RR), heart rate (HR), the clinical respiratory score (CRS), rise of peripheral capillary oxygen saturation (SpO2) and rates of weaning, intubation and intensive care unit (ICU) admission.

Keywords: Bronchiolitis, Emergency department, High-flow nasal cannula, Flow rate

Conditions

  • Non-invasive Ventilation
  • Pediatric Pulmonary Disease

Interventions

DEVICE

Heated humidified high-flow nasal cannula

Non-invasive ventilation with a nasal cannula

Sponsors & Collaborators

  • Ege University

    collaborator OTHER

  • Ali Yurtseven

    lead OTHER

Eligibility

Min Age
1 Day
Max Age
2 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-05-10
Primary Completion
2018-10-31
Completion
2018-10-31

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03859947 on ClinicalTrials.gov