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Atrial Fibrillation in Relationship to Sleep Quality and Plasma Biomarkers

NCT03855540 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2019-03-29

No results posted yet for this study

Summary

A. Compare the plasmatic biomarkers between the cohort with and without AFib.

B. Find sensitive and specific biomarkers that could be used for the diagnostic management of AFib.

C. Compare the quality of sleep between the cohort with and without AFib by the means of sleeping quality questionnaire

Conditions

Interventions

DIAGNOSTIC_TEST

ECHOcardiography

ECHO parameters 1. LA diameter 2. LVEDD 3. LVEF 4. Diastolic dysfunction 5. Valvular disease

DIAGNOSTIC_TEST

Peripheral blood samples for plasmatic biomarkers

1. Coagulation * D - dimer * Fibrinogen 2. Inflammation and fibrosis * Hs - CRP * AGEs * Soluble RAGE 3. Hemodynamics (LA stretch) * Apelin * NT - proBNP * Hs - troponin 4. MiRNA * miRNA - 1 * miRNA - 133 * miRNA - 29b * miRNA - 208a * miRNA - 208b * miRNA - 499

DIAGNOSTIC_TEST

Athens insomnia scale questionnaire

Athens insomnia scale questionnaire

DIAGNOSTIC_TEST

ECG Holter monitor

Patient receives ECG Holter monitor if included to the control group

DIAGNOSTIC_TEST

ECG event recorder

Patient receives ECG event recorder for twice daily (or if symptoms), 90 seconds duration ECG monitoring if included to the control group

Sponsors & Collaborators

  • Premedix Academy

    lead OTHER

Principal Investigators

  • Allan Bohm, MD · The National Institution of Cardiovascular Diseases

  • Stefan Farsky, Associate professor · Slovak league against hypertension

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-11
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • Slovakia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03855540 on ClinicalTrials.gov