MedTrace Logo

Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy

NCT06080503 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 67

Last updated 2025-11-26

No results posted yet for this study

Summary

To compare the acute tolerance of highly conformal hypofractionated versus conventional radiotherapy.

Conditions

  • Laryngeal Carcinoma

Interventions

RADIATION

LT-SABR

42.5 Gy in 5 fractions Low-risk: twice/week Moderate-risk: weekly

RADIATION

IMRT

63 Gy in 28 fractions (T1) 65.25 Gy in 29 fractions (T2)

Sponsors & Collaborators

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • David Sher, MD, MPH · University of Texas Southwestern Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-14
Primary Completion
2028-11-01
Completion
2029-03-14
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06080503 on ClinicalTrials.gov