Study of Anti-CD19 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma
NCT03690310 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 9
Last updated 2019-01-31
Summary
This is a single-centre, single-arm and open-label study to investigate the safety and efficacy of anti CD19 CAR NK cells in patients with relapsed refractory B cell lymphoma.
Conditions
- Refractory B-Cell Lymphoma
Interventions
- BIOLOGICAL
-
Anti-CD19 CAR NK Cells
Anti-CD19 CAR NK Cells injection
Sponsors & Collaborators
-
Allife Medical Science and Technology Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-03-31
- Primary Completion
- 2020-11-30
- Completion
- 2021-11-30
More Related Trials
-
The Safety and Efficacy of CART-19 Cells in Relapse and Refractory Patients With CD19+ B-cell Lymphoma
NCT03101709 ·Status: UNKNOWN ·Phase: PHASE1
-
CAR-T Treatment for Relapse / Refractory Type Safety and Effectiveness of Lymphoma
NCT03488160 ·Status: UNKNOWN ·Phase: NA
-
Safety and Efficiency Study of CD19-PD1-CART Cell in Relapsed/Refractory B Cell Lymphoma
NCT04163302 ·Status: UNKNOWN ·Phase: PHASE2
-
Exploratory Clinical Study of CD19-targeted CAR-T and CAR-DC in the Treatment of Relapsed and Refractory B-cell Lymphoma
NCT05585996 ·Status: RECRUITING ·Phase: PHASE1
-
CART-19 Cells for R/R B-cell Lymphoma
NCT03391726 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
CD19 CART Cells for Patients With Relapse and Refractory CD19+ B-cell Lymphoma.
NCT03146533 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
L218CAR19 in Patients With Relapsed/Refractory B-cell Lymphoma
NCT06478381 ·Status: RECRUITING ·Phase: PHASE1
-
MC-19PD1 CAR-T in Relapsed or Refractory B Cell Lymphoma
NCT03932955 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of A-319 in Patients With Relapsed or Refractory B-cell Lymphoma
NCT04056975 ·Status: UNKNOWN ·Phase: PHASE1
-
A Clinical Study Exploring CT1194C in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
NCT07068906 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
PD1-CD19-CART in Patients With r/r B-cell Lymphoma
NCT04213469 ·Status: COMPLETED ·Phase: NA
-
Safety and Clinical Activity of ThisCART19 in Patients With r/r Non-Hodgkin's B Cell Lymphoma
NCT05106907 ·Status: UNKNOWN ·Phase: PHASE1
-
Sequential Low-dose Decitabine With PD-1/CD28 CD19 CAR-T in Relapsed or Refractory B-cell Lymphoma
NCT04850560 ·Status: UNKNOWN ·Phase: PHASE1
-
Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia
NCT05563545 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Anti-CD19 CAR-T Cell Immunotherapy for Refractory /Relapsed B Cell Malignancies
NCT03191773 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Clinical Research of CD19 Targeted CAR-T Cell in Relapsed/Refractory B Cell Lymphoma
NCT06180174 ·Status: RECRUITING ·Phase: PHASE1
-
Cytoplasmic Activated PD-1 CAR T Cells in Refractory/Relapsed B Cell Lymphoma
NCT03540303 ·Status: UNKNOWN ·Phase: PHASE1
-
CART-19 FOR Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)
NCT03544021 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
CD19-targeted CAR T Cells for Relapsed and Refractory (R/R) Large B-cell Lymphoma
NCT06149169 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Single-center Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LCAR-L10D Cell Formulations Targeting CD19 and CD22 in Patients With CD19- and/or CD22-Positive Relapsed/Refractory B-cell Lymphoma
NCT03593109 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of C-CAR039 in Subjects With Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma
NCT05149391 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Refractory or Relapsed B Cell Lymphoma
NCT05776407 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
CD19 Targeted Universal Chimeric Antigen Receptor T Cells Injection for CD19+ Refractory/Relapsed B-cell Malignancies
NCT05105867 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Safety and Efficacy of Sequential CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Lymphoma
NCT05651100 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Anti-CD19-CAR-T Cells in Subjects With Relapsed/Refractory B Cell Malignancies
NCT06532630 ·Status: RECRUITING ·Phase: EARLY_PHASE1