Etiology and Treatment of Neonatal Seizure
NCT03822741 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000
Last updated 2026-03-16
Summary
Genetic diagnosis for neonates suffering from epilepsy has important implications for treatment, prognosis, and development of precision medicine strategies. Investigator performed exome sequencing (ES) or targeted sequencing on neonates with seizure onset within the first month of life. Investigator subgrouped our patients based on the onset age of seizure into neonatal and before 1 year (1-12 months), to compare the clinical and genetic features and treatment strategies.
Conditions
- Seizures
- Seizure Disorder
- Seizure Newborn
- Seizure Generalized
Sponsors & Collaborators
-
Children's Hospital of Fudan University
lead OTHER
Principal Investigators
-
Wenhao Zhou, Doctor · Children's Hospital of Fudan University
Eligibility
- Max Age
- 12 Months
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-08
- Primary Completion
- 2026-12-30
- Completion
- 2026-12-30
Countries
- China
Study Locations
More Related Trials
-
Ketogenic Diet for Child Epilepsy and Seizure Control
NCT00004729 ·Status: COMPLETED ·Phase: NA
-
Blood Sugars in Children With Idiopathic Seizures.
NCT00279851 ·Status: WITHDRAWN
-
The Potential of a Low Glutamate Diet as a Treatment for Pediatric Epilepsy
NCT04545346 ·Status: COMPLETED ·Phase: NA
-
Molecular Genetics in Infantile Spasms
NCT02885389 ·Status: COMPLETED
-
Predictors of Drug Resistant Epilepsy Among Pediatric Patients
NCT07241754 ·Status: NOT_YET_RECRUITING
-
Childhood Convulsive Status Epilepticus Management In A Resource Limited Setting
NCT03650270 ·Status: COMPLETED ·Phase: PHASE3
-
Utility of Laboratory Testing for Children With Seizure in Emergency Department
NCT01123746 ·Status: COMPLETED
-
Lacosamide in Neonatal Status Epilepticus
NCT05291455 ·Status: UNKNOWN ·Phase: PHASE3
-
The Prevalence and Risk Factors of Coagulopathy in Pediatric Epilepsy Surgery Patients
NCT05675254 ·Status: COMPLETED
-
Genetic Study for Infantile Onset Diabetes Mellitus
NCT03519217 ·Status: UNKNOWN
-
Assessment of Pre Hospital Rescue Intervention for Seizure in Pediatric Patients
NCT06723431 ·Status: NOT_YET_RECRUITING
-
Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
NCT02216500 ·Status: RECRUITING ·Phase: NA
-
Feasibility, Tolerability and Efficacy of the Ketogenic Diet in Children With Drug-resistant Epilepsy in South Vietnam
NCT05697887 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency Disorder
NCT06447675 ·Status: COMPLETED ·Phase: NA
-
Prevention of Epilepsy by Reducing Neonatal Encephalopathy
NCT04054453 ·Status: UNKNOWN ·Phase: NA
-
Respiratory Physiology in Children With Febrile Seizures.
NCT01906619 ·Status: COMPLETED
-
RCT of the Efficacy of the Ketogenic Diet in the Treatment of Epilepsy
NCT00564915 ·Status: COMPLETED ·Phase: PHASE4
-
Ketogenic Diet in Infants With Epilepsy (KIWE)
NCT02205931 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Magnesium Supplementation for Children With Drug Resistant Idiopathic Epilepsy
NCT02982824 ·Status: COMPLETED ·Phase: NA
-
Ultra High Field MRI of Focal Pediatric Epilepsy
NCT03318237 ·Status: TERMINATED
-
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis
NCT03307304 ·Status: RECRUITING
-
Exogenous Ketone Esters for Refractory Status Epileptics
NCT05674552 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment
NCT00004758 ·Status: COMPLETED ·Phase: PHASE2
-
Ketogenic Diet for New-Onset Absence Epilepsy
NCT04274179 ·Status: RECRUITING ·Phase: PHASE3
-
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood
NCT02225041 ·Status: COMPLETED