MedTrace Logo

The Role of High-flow Nasal Cannula Therapy in the Treatment of Acute Carbon Monoxide Poisoning

NCT03818841 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 96

Last updated 2019-02-06

No results posted yet for this study

Summary

The aim of the study is to test whether oxygen therapy delivered through high-flow nasal cannula devices in patients admitted to the emergency department for acute carbon monoxide poisoning is superior to the non-rebreathing oxygen face mask therapy with a 15 L/minute oxygen flow (currently the first-line therapy), in terms of reduction of carboxyhemoglobin (COHb) concentration and delayed neurological sequelae incidence.

Conditions

  • Carbon Monoxide Poisoning

Interventions

DEVICE

High-flow nasal cannula device

Patients will be randomly allocated to this treatment

DEVICE

Non-rebreathing oxygen mask group

Patients will be randomly allocated to this treatment

Sponsors & Collaborators

  • Università degli Studi del Piemonte Orientale Amedeo Avogadro

    lead OTHER

Principal Investigators

  • Luigi M Castello, MD · A.O.U. Maggiore della Carità di Novara

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-01
Primary Completion
2022-02-01
Completion
2022-02-01

Countries

  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03818841 on ClinicalTrials.gov