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Study of Accurate Diagnosis and Treatment of Peutz-Jeghers Syndrome

NCT03806075 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2019-01-16

No results posted yet for this study

Summary

The mutation of STK11 has been regcognized to be the major cause of Peutz-Jeghers syndrome (PJS).The aim of this study was to confirm the mutation rate of gene associated with gastrointestinal malignancies,including STK11, APC,PMS1,et al. Furtherly, the investigators analyze the association of STK11 with gut microbiota.

Conditions

  • Peutz-Jeghers Syndrome

Interventions

BEHAVIORAL

Second generation sequencing

Firstly, all Peutz-Jeghers patients accept second generation gene sequencing with their blood specimen

BEHAVIORAL

16s rRNA gene sequencing

Secondly, All patients and Health persons accepted 16s rRNA gene sequencing with their feces specimen

Sponsors & Collaborators

  • Yiqi Du

    lead OTHER

Principal Investigators

  • Yiqi Du, Ph.D. · Changhai Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
5 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-03-01
Primary Completion
2021-09-01
Completion
2021-09-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03806075 on ClinicalTrials.gov