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Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)

NCT02656134 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2016-01-14

No results posted yet for this study

Summary

Background and study aim The relative risks of duodenal adenocarcinoma and ampullary carcinoma in Familial Adenomatous Polyposis (FAP) have been estimated 100 to 330 times higher than in general population. However risk factors, including a genotype-phenotype association for duodenal cancer in FAP has not been fully understood. The aim of this study is to determine risk factors associated with the development of advanced duodenal polyposis and ampullary adenomas in colectomized patients with FAP.

Conditions

Interventions

PROCEDURE

Duodenoscopy and enteroscopy

All patients will undergo duodenoscopy and classified according to Spigelman. Patients classified as Spigelman III and IV will undergo enteroscopy.

GENETIC

Molecular analysis.

DNA analysis

Sponsors & Collaborators

  • University of Sao Paulo

    lead OTHER

Principal Investigators

  • Marianny Sulbaran, MD · PhD

Eligibility

Min Age
15 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2016-09-30
Completion
2016-12-31

Countries

  • Brazil

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02656134 on ClinicalTrials.gov