Apatinib Combined With Radiotherapy in Patient With BM From Drive Gene Negative NSCLC
NCT03801200 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2022-02-08
Summary
The purpose of this study is to evaluate the efficacy and safety of concurrent radiotherapy with Apatinib in patients with Brain Metastases from drive gene wide-type Non-small-cell Lung Cancer (NSCLC).
Conditions
Interventions
- DRUG
-
Apatinib
radiotherapy with Apatinib
Sponsors & Collaborators
-
Hubei Cancer Hospital
lead OTHER
Principal Investigators
-
Desheng Hu · Associate dean
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-10
- Primary Completion
- 2021-09-10
- Completion
- 2023-09-10
Countries
- China
Study Locations
More Related Trials
-
An Exploration of Apatinib Combined With S-1 in Patients With Advanced Non-small Cell Lung Cancer
NCT03129256 ·Status: COMPLETED ·Phase: PHASE2
-
Maintenance Therapy of Apatinib After Chemoradiotherapy in Metastatic Nasopharyngeal Carcinoma
NCT03180476 ·Status: COMPLETED ·Phase: PHASE2
-
Appatinib Combined With S-1 in the Treatment of Small Cell Lung Cancer
NCT04128800 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With Vinorelbine for Non-driver Gene Mutation Non-small Cell Lung Cancer
NCT03652857 ·Status: COMPLETED ·Phase: PHASE2
-
Optimizing the Therapeutic Dose of Apatinib Mesylate Tablets in Patients With Lung Cancer by Dose Titration:A Real World Exploratory Study
NCT03594682 ·Status: UNKNOWN ·Phase: NA
-
Apatinib in Combination With Docetaxel for Patients With Advanced NSCLC
NCT03411967 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy and Safety of Apatinib Combined With Etoposide in Heavily Pretreated Advanced Non-small Cell Lung Cancer
NCT02733107 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib in the Treatment of Patients With EGFR T790M-Negative NSCLC
NCT03389256 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With EGFR-TKI for Advanced Slow-progressed EGFR-TKI Resistant NSCLC
NCT03428022 ·Status: UNKNOWN ·Phase: PHASE3
-
Compare Apatinib Plus Chemotherapy Drug Versus Chemotherapy Drug as Second-line Treatment in NSCLC
NCT03256721 ·Status: TERMINATED ·Phase: PHASE2
-
Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases
NCT07304739 ·Status: RECRUITING ·Phase: PHASE2
-
Apatinib Combined With Chemotherapy for NSCLC Patients Without T790M Mutation
NCT03758677 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With SHR-1210 Injection in the Treatment of Patients With Removable IB-IIIA NSCLC
NCT04133337 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Study of Apatinib in RET Fusion Positive Advanced Non-small Cell Lung Cancer
NCT02540824 ·Status: UNKNOWN ·Phase: PHASE2
-
The Combination of Apatinib and Camerlizumab for Advanced Lung Cancer Patients With Muti-line Therapy
NCT04782622 ·Status: UNKNOWN
-
Maintenance Treatment of Apatinib in Nasopharyngeal Carcinoma
NCT03130270 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combine With EGFR-TKI for Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
NCT03050411 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of Apatinib in Patients With Advanced Non-squamous and Non-small Cell Lung Cancer
NCT01270386 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of SHR-1210 in Combination With Apatinib in Advanced Non-Small Cell Lung Cancer(NSCLC)
NCT03083041 ·Status: COMPLETED ·Phase: PHASE2
-
A Single-arm, Multicenter, Prospective Phase II Clinical Study of Apatinib in Combination With Adebrelimab and EC Regimen in the First-line Treatment of Extensive Small Cell Lung Cancer
NCT06786312 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
The Efficacy and Safety of Apatinib Monotherapy in Maintenance Treatment of Extensive-stage Small-cell Lung Cancer
NCT03129698 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With Docetaxel Monotherapy as Second-line Therapy of Advanced EGFR WT, Non-squamous NSCLC
NCT02852798 ·Status: UNKNOWN
-
Phase Ⅲ Trial of WBRT Versus Erlotinib Concurrent Whole-brain Radiation Therapy as first-line Treatment for Patients With Multiple Brain Metastases From Non-small-cell Lung Cancer(ENTER): a Multicentre, Open-label, Randomised Study
NCT01887795 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Apatinib as 3rd/4th Line Treatment in Patients With Advanced Non-Squamous Non-small Cell Lung Cancer Harboring Wild-type Epidermal Growth Factor Receptor (EGFR)
NCT02332512 ·Status: UNKNOWN ·Phase: PHASE3
-
Apatinib in the Treatment of Advanced Non-squamous Non-small Cell Lung Cancer
NCT01287962 ·Status: UNKNOWN ·Phase: PHASE3