Apatinib Combined With Docetaxel Monotherapy as Second-line Therapy of Advanced EGFR WT, Non-squamous NSCLC
NCT02852798 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2016-08-03
Summary
This is a clinical study of Apatinib Mesylate Tablets combined with docetaxel monotherapy as second-line therapy of advanced EGFR wild-type, non-squamous, non-small-cell lung cancer.
Conditions
- Nonsquamous Nonsmall Cell Neoplasm of Lung
Interventions
- DRUG
-
Apatinib Combined With Docetaxel
Docetaxel 75 mg/ (m2.d)IV gtt 1h d1 q3w Apatinib Mesylate Tablets : 500 mg qd, 4 weeks as one cycle for continuous drug administration
Sponsors & Collaborators
-
Dongguan People's Hospital
collaborator OTHER_GOV -
Jiangsu ShengDiYa Medicine Co., Ltd.
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-31
- Primary Completion
- 2017-08-31
- Completion
- 2018-08-31
More Related Trials
-
The Efficacy and Drug Resistance Molecular Biology of Apatinib Combined With EGFR-TK1 Treated for Advanced Slow-progressed Non-Small Cell Lung Cancer (NSCLC)
NCT03811054 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With EGFR-TKI for Advanced Slow-progressed EGFR-TKI Resistant NSCLC
NCT03428022 ·Status: UNKNOWN ·Phase: PHASE3
-
Topotecan Plus Apatinib Versus Topotecan Alone as Second-line Therapy in Small-cell Lung Cancer
NCT02980809 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combine With EGFR-TKI for Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
NCT03050411 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of Apatinib Plus Etoposide Capsule as the Therapy of Advanced Small Cell Lung Cancer
NCT03389087 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Effectiveness Study of Chemotherapy in Combination With Erlotinib,or Sequential Erlotinib for Treatment in Patients With NSCLC
NCT02037997 ·Status: UNKNOWN ·Phase: PHASE2
-
SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC.
NCT05020457 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Gefitinib With or Without Apatinib in Patients With Advanced Non-squamous Non-Small-Cell Lung Cancer Harboring EGFR Mutations
NCT02824458 ·Status: UNKNOWN ·Phase: PHASE3
-
Afatinib Combined With Chemotherapy as Conversion Therapy in Unresectable EGFR Sensitive Mutation-positive Stage III NSCLC
NCT06709859 ·Status: RECRUITING ·Phase: PHASE2
-
An Exploration of Apatinib Combined With S-1 in Patients With Advanced Non-small Cell Lung Cancer
NCT03129256 ·Status: COMPLETED ·Phase: PHASE2
-
The Efficacy and Safety of Apatinib Combined With Etoposide in Heavily Pretreated Advanced Non-small Cell Lung Cancer
NCT02733107 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy and Safety of Apatinib in Heavily Pretreated Advanced Non-squamous Non-small Cell Lung Cancer
NCT02515435 ·Status: UNKNOWN ·Phase: PHASE2
-
Compare Apatinib Plus Chemotherapy Drug Versus Chemotherapy Drug as Second-line Treatment in NSCLC
NCT03256721 ·Status: TERMINATED ·Phase: PHASE2
-
First-line Treatment With Dacomitinib Plus Anlotinib for Patients With Advanced NSCLC With EGFR 21L858R Mutations
NCT05271916 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Apatinib Combined With Chemotherapy for NSCLC Patients Without T790M Mutation
NCT03758677 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Clinical Study of Intermittent High Dose of Icotinib in Combination With Docetaxel to Treat Lung Cancer
NCT02191059 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With Vinorelbine for Non-driver Gene Mutation Non-small Cell Lung Cancer
NCT03652857 ·Status: COMPLETED ·Phase: PHASE2
-
EGFR-TKIs Combine Chemotherapy as First-line Therapy for Patients With Advanced EGFR Mutation-positive NSCLC
NCT02886195 ·Status: UNKNOWN ·Phase: PHASE3
-
Study of Apatinib as 3rd/4th Line Treatment in Patients With Advanced Non-Squamous Non-small Cell Lung Cancer Harboring Wild-type Epidermal Growth Factor Receptor (EGFR)
NCT02332512 ·Status: UNKNOWN ·Phase: PHASE3
-
Apatinib in the Treatment of Advanced Non-squamous Non-small Cell Lung Cancer
NCT01287962 ·Status: UNKNOWN ·Phase: PHASE3
-
Erlotinib Versus Gemcitabine/Carboplatin in Chemo-naive Stage IIIB/IV Non-Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Exon 19 or 21 Mutation
NCT00874419 ·Status: COMPLETED ·Phase: PHASE3
-
Appatinib Combined With S-1 in the Treatment of Small Cell Lung Cancer
NCT04128800 ·Status: UNKNOWN ·Phase: PHASE2
-
Pemetrexed Combined With Synchronous Gefitinib as Adjuvent Therapy in Patient With EGFR Mutant Lung Adenocarcinoma
NCT02518802 ·Status: UNKNOWN ·Phase: PHASE3
-
Anti-angiogenesis Combine With EGFR-TKI in Advanced Non-squamous Non Small Cell Lung Cancer
NCT03461185 ·Status: UNKNOWN ·Phase: PHASE2
-
Abivertinib Maleate Versus Geifitinib in Patients With Advanced Non-small Cell Lung Cancer With Sensitive EGFR Mutation
NCT03856697 ·Status: UNKNOWN ·Phase: PHASE3