Characterization of Lipoprotein Composition and Function in Pediatric Psoriasis Before and After Treatment
NCT03791216 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 62
Last updated 2025-07-29
Summary
This study will assess differences in inflammatory proteins, lipoprotein composition, cholesterol efflux and HDL-proteome in moderate-to-severe pediatric psoriasis who at baseline begin systemically administered therapy vs: a) healthy controls; and b) patients with milder psoriasis.
Conditions
Interventions
- OTHER
-
Fasting blood draw for lipid assessments
Fasting blood draw for lipid assessments
Sponsors & Collaborators
-
National Psoriasis Foundation
collaborator OTHER -
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
Children's Hospital of Philadelphia
collaborator OTHER -
Radboud University Medical Center
collaborator OTHER - lead OTHER
Principal Investigators
-
Amy Paller, MD · Northwestern University
Eligibility
- Min Age
- 6 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-12-01
- Primary Completion
- 2025-06-18
- Completion
- 2025-06-18
Countries
- United States
Study Locations
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