MedTrace Logo

Effects of Gum Arabic Supplementation in Hemodialysis Patients

NCT03789708 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2019-01-03

No results posted yet for this study

Summary

Gum Arabic is a naturally produced gummy exudate from Acacia Senegal tree. It's a complex polysaccharide with proven prebiotic properties. Through its effect on intestinal bacteria, it's expected to reduce systemic levels of toxic bacterial metabolites and reduce inflammatory markers.By increasing fecal bacteria mass it's also expected to reduce blood urea level. These changes are potentially beneficial to hemodialysis patients who suffer from disturbed intestinal flora and a chronic inflammatory status. The investigators hypothesize that supplementing the diet of hemodialysis patients with Gum Arabic for four weeks would reduce inflammatory markers, increase total anti-oxidant capacity and reduce blood urea concentration.

Conditions

  • Kidney Failure, Chronic

Interventions

DIETARY_SUPPLEMENT

Gum Arabic

Instantly soluble granules of Gum Arabic; 100% Acacia Senegal

OTHER

Placebo

Maltodextrin powder, easily soluble

Sponsors & Collaborators

  • National Center for Kidney Diseases and Surgery

    collaborator UNKNOWN

  • Almughtaribeen University

    collaborator UNKNOWN

  • University of Khartoum

    lead OTHER

Principal Investigators

  • Sarra Elamin, MD · Consultant Nephrologist

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-11-01
Primary Completion
2019-03-01
Completion
2019-06-01

Countries

  • Sudan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03789708 on ClinicalTrials.gov