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Effects of N-acetylcysteine on Muscle Fatigue in Hemodialysis

NCT00440869 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2010-03-03

No results posted yet for this study

Summary

The purposes of the study are to determine whether oxidative stress causes the muscle of dialysis patients to tire more quickly than muscle of people without kidney disease and to determine whether treatment with N-acetylcysteine, an antioxidant, can improve muscle endurance.

Conditions

  • End-Stage Renal Disease
  • Dialysis
  • Hemodialysis

Interventions

DIETARY_SUPPLEMENT

N-acetylcysteine

600 mg po bid

DIETARY_SUPPLEMENT

placebo

bid oral dosing

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    lead NIH

Principal Investigators

  • Kirsten L Johansen, MD · University of California, San Francisco, San Francisco VA Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-03-31
Primary Completion
2009-12-31
Completion
2009-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00440869 on ClinicalTrials.gov