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Ischemic Postconditioning in STEMI Patients Treated With Primary PCI

NCT03787745 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1800

Last updated 2026-03-30

No results posted yet for this study

Summary

In a prospective, randomized clinical trial the iPOST2 trial will determine whether ischemic postconditioning reduces reperfusion injury and this will translate into improved clinical outcome of heart failure and death for STEMI patients who present with TIMI0-1 undergoing primary PCI

Conditions

  • ST Segment Elevation Myocardial Infarction

Interventions

PROCEDURE

Ischemic postconditioning

After 60 seconds of reperfusion, ischemic postconditioning with an adequately sized balloon (60 reperfusion/60 seconds re-occlusion, four cycles) will be performed

PROCEDURE

Conventional

State of the art primary PCI, however thrombectomy is not allowed

Sponsors & Collaborators

  • Rigshospitalet, Denmark

    lead OTHER

Principal Investigators

  • Thomas Engstrøm, DMSci · Rigshospitalet, Denmark

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-04
Primary Completion
2026-05-31
Completion
2033-01-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03787745 on ClinicalTrials.gov