Brain and Genetic Predictors of Individual Differences in Pain and Analgesia
NCT03781570 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 541
Last updated 2025-06-04
Summary
The purpose of the study is to gain a better understanding of pain processing in the brain. Our understanding of how pain is processed in the brain is limited. We are testing for individual differences in pain perception and emotion.
Conditions
- Pain, Acute
Interventions
- BEHAVIORAL
-
Placebo Cream
In the Placebo intervention, participants are given an inert cream with instructions that it is "Prodicaine, an effective pain-relieving drug". The cream is applied to two fingers on the left hand.
- BEHAVIORAL
-
Control Cream
In the Control intervention, participants are given an inert cream with instructions that it is "a control cream with no effects" . The cream is applied to two fingers on the left hand.
Sponsors & Collaborators
-
QIMR Berghofer Medical Research Institute
collaborator OTHER -
Trustees of Dartmouth College
lead OTHER
Principal Investigators
-
Tor Wager, PHD · University of Colorado, Boulder
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-11-07
- Primary Completion
- 2023-10-01
- Completion
- 2023-10-01
Countries
- United States
Study Locations
More Related Trials
-
Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain
NCT05963451 ·Status: RECRUITING
-
The Neurobiology of Expectancy and Pain Perception
NCT01575106 ·Status: COMPLETED ·Phase: NA
-
Investigating the Role of Brain-derived Neurotrophic Factor (BDNF) Between Pain and Other Neuronal Disease
NCT03606915 ·Status: COMPLETED
-
Identifying Neuroimaging Biomarkers, Demographic, Personality and Sensory Factors for Predicting Extreme Pain Responses to Various Experimental Pain Stimulations in Healthy Subjects
NCT03436264 ·Status: UNKNOWN
-
Detection of EEG-Based Biomarkers of Chronic Low Back Pain
NCT06025201 ·Status: RECRUITING ·Phase: NA
-
Shifting Away From Pain: Neurocognitive Approach to Explain and Predict Recovery Following Whiplash Injury
NCT05161767 ·Status: TERMINATED
-
Treatment Of Chronic Pain Using Real Time fMRI
NCT00528346 ·Status: UNKNOWN ·Phase: PHASE2
-
Real-Time fMRI Feedback Effects on Pain Perception
NCT01588197 ·Status: COMPLETED ·Phase: NA
-
Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning
NCT06234917 ·Status: COMPLETED ·Phase: NA
-
Visual Stimulation for Pain Relief
NCT06276881 ·Status: COMPLETED ·Phase: NA
-
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain
NCT03003715 ·Status: COMPLETED ·Phase: NA
-
Characterization & Treatment of Chronic Pain After Moderate to Severe TBI
NCT03739307 ·Status: COMPLETED
-
Mental Processes for Rating Pain Intensity
NCT06822764 ·Status: ENROLLING_BY_INVITATION
-
Differences in Brain Derived Neurotrophic Factor Levels Between Chronic and Asymptomatic Pain Patients
NCT05736575 ·Status: RECRUITING
-
Pilot Study Evaluating Neuro-Imaging Correlates of Epigenetic Finding in Prediction of Chronic Postsurgical Pain
NCT04681183 ·Status: ACTIVE_NOT_RECRUITING
-
Brain Imaging and Pain: Analysis of Placebo Analgesia
NCT01409538 ·Status: COMPLETED ·Phase: PHASE1
-
Using Functional MRI to Evaluate Cognitive Behavioral Therapy Treatment Response in Adults With Chronic Pain
NCT00796536 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Augmented Cerebral Pain Processing in Chronic, Unexplained Pain: a fMRI Study
NCT00463177 ·Status: COMPLETED
-
The Use of Resting State, fMRI and DTI in the Identification of Chronic Pain Conditions
NCT02987933 ·Status: UNKNOWN
-
Transcranial Magnetic Stimulation for Facial Pain
NCT02633306 ·Status: COMPLETED ·Phase: NA
-
Neuroimaging of Pain: Changes in Regional Brain Functioning Associated With Amplified Pain and Intensive Treatment
NCT03703921 ·Status: COMPLETED
-
Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes
NCT04310735 ·Status: COMPLETED ·Phase: NA
-
Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
NCT04603417 ·Status: COMPLETED ·Phase: NA
-
Pain Neuroscience Education for Depression
NCT04023435 ·Status: COMPLETED ·Phase: NA
-
A Methodology Study Of Brain Imaging Of Pain-Killers In Post-Traumatic Neuropathic Pain Patients
NCT00610155 ·Status: COMPLETED ·Phase: NA