Brain and Genetic Predictors of Individual Differences in Pain and Analgesia

NCT03781570 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 541

Last updated 2025-06-04

Study results available
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Summary

The purpose of the study is to gain a better understanding of pain processing in the brain. Our understanding of how pain is processed in the brain is limited. We are testing for individual differences in pain perception and emotion.

Conditions

  • Pain, Acute

Interventions

BEHAVIORAL

Placebo Cream

In the Placebo intervention, participants are given an inert cream with instructions that it is "Prodicaine, an effective pain-relieving drug". The cream is applied to two fingers on the left hand.

BEHAVIORAL

Control Cream

In the Control intervention, participants are given an inert cream with instructions that it is "a control cream with no effects" . The cream is applied to two fingers on the left hand.

Sponsors & Collaborators

  • QIMR Berghofer Medical Research Institute

    collaborator OTHER
  • Trustees of Dartmouth College

    lead OTHER

Principal Investigators

  • Tor Wager, PHD · University of Colorado, Boulder

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-07
Primary Completion
2023-10-01
Completion
2023-10-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03781570 on ClinicalTrials.gov