Comparison of Inflammatory Profiles and Regenerative Potential in Alcoholic Liver Disease
NCT03773887 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 450
Last updated 2026-05-22
Summary
The main objective of this study is the comparison of the profile of the pro-inflammatory cytokines at the patients suffering from an alcoholic hepatitis to that of two groups witnesses: patients suffering from an alcoholic cirrhosis and unhurt patients of chronic liver disease
Conditions
- Liver Diseases
- Acute on Chronic Hepatic Failure
Interventions
- OTHER
-
collection of liver biopsies collection of blood samples
blood and ascites samples; extraction of explants, hepatic resection parts; hepatic parenchyma on liver biopsies
Sponsors & Collaborators
-
University Hospital, Lille
lead OTHER
Principal Investigators
-
Philppe Mathurin, MD,PhD · University Hospital, Lille
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-12-25
- Primary Completion
- 2027-09-30
- Completion
- 2027-09-30
Countries
- France
Study Locations
More Related Trials
-
Metabolic Associated Fatty Liver Disease in Patients With Chronic Glomerular Disease
NCT06691529 ·Status: NOT_YET_RECRUITING
-
Single Cell Landscape of HBV-related Acute-on-chronic Liver Failure Patients
NCT06865859 ·Status: RECRUITING
-
Role of Coagulation, Inflammation and Vessels in Chronic Liver Disease
NCT05865691 ·Status: RECRUITING
-
Prospective Studies on Immunopathogenesis of Liver Fibrosis
NCT04943978 ·Status: RECRUITING
-
Cytokines and the Risk of Infection in Liver Cirrhosis
NCT00857181 ·Status: TERMINATED
-
Development and Characterization of Functional Assays for the Analysis of Inflammation Signaling Pathways
NCT06971289 ·Status: NOT_YET_RECRUITING
-
Patterns and Outcome of Autoimmune Related Liver Disease
NCT03898414 ·Status: COMPLETED
-
Immunological Measurement of Aspartate/Alanine Aminotransferase
NCT03562585 ·Status: COMPLETED
-
Prospective Clinical Study of the Role of the Immune Response, in Relation to Diet, in Patients Affected by Either Chronic Hepatitis C Virus (HCV) Infection or Non Alcoholic Fatty Liver Disease (NAFLD)
NCT02038387 ·Status: UNKNOWN ·Phase: NA
-
Identification and Verification of Neutrophil Extracellular Trap Net Related Markers in Acute-on-chronic Liver Failure
NCT05909319 ·Status: UNKNOWN
-
A Cross-sectional Study on the Association of Peptidoglycan Fragments Derived From Gut Microbiota With Alcohol Liver Disease
NCT07284862 ·Status: COMPLETED
-
Assessment of the Predictive Value of Fecal Calprotectin for the Outcome of Severe Alcoholic Hepatitis
NCT02808663 ·Status: COMPLETED ·Phase: NA
-
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis
NCT00160940 ·Status: UNKNOWN
-
sgp130 in Chronic Human Liver Disease
NCT00770198 ·Status: COMPLETED
-
Monocytic Expression of HLA-DR After Liver Transplantation
NCT03995537 ·Status: COMPLETED
-
The Association Between Gene Polymorphisms and Infectious Complications After Liver Surgery
NCT00887887 ·Status: COMPLETED
-
Il-17 Levels in Intrahepatic Cholestasis of Pregnancy
NCT01898832 ·Status: UNKNOWN
-
Correlation Between Cytokines and Hepatic Histology in Patients Infected by HIV-1 and the Hepatitis-C Virus
NCT00499434 ·Status: UNKNOWN
-
Study of the Clinical Features of Autoimmune Hepatitis
NCT02994537 ·Status: UNKNOWN
-
Specific Biomarkers of Immune-mediated Hepatitis Secondary to Immune Checkpoint Inhibitors
NCT06470997 ·Status: RECRUITING
-
Integrated Phenotyping of the Gut-plAtelet-Liver AXIS in the Progression of Chronic Liver Disease (iGAL-AXIS)
NCT06623084 ·Status: NOT_YET_RECRUITING
-
Studying Non Alcoholic Fatty Liver Disease and Liver Fibrosis Among Systemic Lupus Erythematosus Patients At Assiut University Hospital
NCT06601361 ·Status: NOT_YET_RECRUITING
-
Biomarkers to Predict the Success of Immunosuppression Withdrawal in Autoimmune Hepatitis
NCT03711669 ·Status: UNKNOWN
-
French National MICMAF Cohort
NCT05895890 ·Status: RECRUITING
-
Effect of High-protein High-fiber Diet in Patients With Autoimmune Hepatitis
NCT01655121 ·Status: COMPLETED ·Phase: NA