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Intraoperative Versus CT Guided Celiac Plexus Neurolysis in Unresectable Pancreatic Cancer

NCT03770247 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 76

Last updated 2019-12-24

No results posted yet for this study

Summary

Many studies had stated that the coeliac plexus neurolysis (CPN) is a safe and effective treatment method of pain associated with pancreatic cancer. The neurolytic injectate is usually alcohol 50-100%; however, phenol \>5% is also possible to use. Nowadays, there are several techniques to access the coeliac plexus (per cutaneous using fluoroscopy or computed tomographic imaging (CT), surgical and endoscopic ultrasound). However, the percutaneous computed tomography guided technique is the gold standard technique, it has multiple drawbacks as availability and cost of imaging modality, exposure to radiation and multiple complications.Surgical technique in spite of being easy, cheap but there is a controversy about its efficacy. Also there is no head to head comparison between the surgical technique and the percutaneous technique.In this study we hypothesized that intraoperative technique has the same efficacy of percutaneous celiac block technique with less complication and cost

Conditions

  • Pain, Chronic

Interventions

PROCEDURE

Intraoperative celiac plexus neurolysis

neurolysis of celiac plexus by intraoperative techniques

PROCEDURE

CT guided celiac plexus neurolysis

Neurolysis of celiac plexus percutaneously by CT guidance

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Tarek M. Shams, MD · : Professor of Anesthesia and Surgical Intensive Care

  • Mahmoud M. Elsedeiq, MSc · assistan lecturer of Anesthesia and Surgical Intensive Care

  • Mohamed A. Ghanim, MD · Assistant Professor of Anesthesia and Surgical Intensive Care

  • Ibrahim I. Abd El-basir, MD · Lecturer of Anesthesia and Surgical Intensive Care

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2019-09-01
Completion
2019-10-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03770247 on ClinicalTrials.gov