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Postoperative Progression of the Disease Following Extensive Versus Limited Mesenteric Excision for Crohn's Disease

NCT03769922 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 116

Last updated 2019-02-27

No results posted yet for this study

Summary

The study evaluates whether there is a reduction in the rate of postoperative progression of the disease following extensive mesenteric excision (EME), when compared to that of limited mesenteric excision (LME), in patients undergoing ileocolic resection for Crohn's disease. Half of participants will receive EME, while the other half will receive LME.

Conditions

  • Postoperative Surgical Recurrence

Interventions

PROCEDURE

Extensive mesenteric resection

The mesentery is resected avoiding the root region.

PROCEDURE

Limited mesenteric excision

The mesentery is retained.

Sponsors & Collaborators

  • University Hospital of Limerick

    collaborator OTHER

  • The Cleveland Clinic

    collaborator OTHER

  • Sixth Affiliated Hospital, Sun Yat-sen University

    collaborator OTHER

  • Sir Run Run Shaw Hospital

    collaborator OTHER

  • Jinling Hospital, China

    lead OTHER

Principal Investigators

  • Zhu Weiming · Jinling Hospital, Nanjing, China.

  • John Calvin Coffey · University Hospital Limerick, Limerick, Ireland.

  • Luca Stocchi · The Cleveland Clinic

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
16 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-18
Primary Completion
2024-01-31
Completion
2025-01-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03769922 on ClinicalTrials.gov