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Concordance Between FFR and iFR for the Assessment of Intermediate Lesions in the Left Main Coronary Artery. A Prospective Validation of a Default Value for iFR

NCT03767621 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2025-03-05

No results posted yet for this study

Summary

The assessment of Left Main Coronary Artery (LMCA) lesions by means of coronary angiography renders serious limitations.

Studies with a limited number of patients have shown that a value of FFR (Fractional Flow Reserve) above 0.80 identify a low risk of events in case of not performing revascularization in patients with intermediate stenosis in the LMCA. Although iFR (Instant wave Free Ratio) has recently been found equivalent to FFR The demonstration of the prognostic utility of iFR in patients with LMCA intermediate lesions could have an important clinical impact and justify its systematic use for the treatment decision in these high-risk patients.

Conditions

  • Coronary Artery Disease
  • Left Main Coronary Artery Stenosis
  • Left Main Coronary Artery Disease
  • Restenosis, Coronary

Interventions

OTHER

Indication of revascularization

Device: iFR/FFR

Sponsors & Collaborators

  • Fundación EPIC

    lead OTHER

Principal Investigators

  • José María de la Torre, PhD, MD · Hospital Universitario Marqués de Valdecilla

  • Oriol Rodríguez Leor, PhD, MD · Germans Trias i Pujol Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-19
Primary Completion
2026-06-30
Completion
2026-11-30

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03767621 on ClinicalTrials.gov