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Comparison of Percutaneous Coronary Intervention Optimization With Fractional Flow Reserve Versus Intravascular Ultrasound in the Treatment of Long Coronary Artery Lesions

NCT05732324 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 154

Last updated 2023-02-22

No results posted yet for this study

Summary

A single center, prospective, observational study to compare fractional flow reserve (FFR) and intravascular ultrasound (IVUS) percutaneous coronary intervention (PCI) optimization strategies on the functional PCI result (assessed with FFR) immediately post PCI and at 9-12 months after the treatment of long coronary artery lesions.

Conditions

Interventions

PROCEDURE

IVUS guided PCI optimization

PCI to long lesion will be optimized according to the IVUS.

PROCEDURE

FFR guided PCI optimization

PCI to long lesion will be optimized according to the FFR.

DIAGNOSTIC_TEST

FFR measurement

Fractional flow reserve protocol will be applied for both FFR-guided and IVUS-guided PCI groups. FFR will be measured according to the standard practice using intravenous adenosine. FFR will be recorded before PCI at the distal third of the coronary artery and after PCI at the same location. In FFR optimization group more than one post PCI FFR measurements could be acquired if the operators performed additional optimization. In IVUS optimization group only one post PCI FFR measurement will be recorded after which the procedure will be considered to be finished, and no further interventions will be undertaken. The same FFR measurements will be performed at 9-12 months follow-up.

Sponsors & Collaborators

  • Vilnius University

    collaborator OTHER

  • Vilnius University Hospital Santaros Klinikos

    lead OTHER

Principal Investigators

  • Giedrius Davidavicius, PhD, prof · Vilnius University Hospital Santaros Klinikos

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-09-01
Primary Completion
2022-03-31
Completion
2022-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05732324 on ClinicalTrials.gov