The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
NCT03761446 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2025-03-13
Summary
The goal of this study is to determine the impact of pre-diabetes and type 2 diabetes on muscle atrophy during a period of bed rest and recovery of muscle mass, strength, and physical function following bed rest.
Conditions
- Type 2 Diabetes
- Muscle Atrophy
- Aging
- Sedentary Behavior
- Pre-diabetes
Interventions
- BEHAVIORAL
-
Bed rest
The participant will remain in bed rest for 10 complete days.
Sponsors & Collaborators
-
AdventHealth Translational Research Institute
lead OTHER
Principal Investigators
-
Paul Coen, PhD · Translational Research Institute for Metabolism and Diabetes
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 60 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-03-18
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- United States
Study Locations
More Related Trials
-
Mechanisms of Fatigability With Diabetes
NCT04442451 ·Status: RECRUITING ·Phase: NA
-
Resistance Training in Diabetic Elder Patients
NCT01638351 ·Status: COMPLETED ·Phase: NA
-
Exercise Training and Glucose Metabolism in Aging
NCT00701051 ·Status: COMPLETED ·Phase: NA
-
The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults
NCT05468255 ·Status: RECRUITING ·Phase: NA
-
Results of Progressive Resistance Training in Older Type 2 Diabetic Patients With Sarcopenia
NCT06337357 ·Status: RECRUITING ·Phase: NA
-
Abdominal Muscle Exercises on Nocturia and Sleep Quality in Women With Type 2 Diabetes
NCT05222477 ·Status: COMPLETED ·Phase: NA
-
Mitochondrial Impairment in Muscle Insulin Resistance
NCT00222924 ·Status: COMPLETED ·Phase: NA
-
Effects of Physical Exercise in Type 2 Diabetics
NCT01095068 ·Status: TERMINATED ·Phase: NA
-
Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes
NCT04754581 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
VLCD & Adjuvant Exercise Effect in Overweight Diabetic Men
NCT04957589 ·Status: COMPLETED ·Phase: NA
-
Secondary Prevention in Type 2 Diabetes: Comparison of Two Different Resistance Exercise Training Protocols
NCT01218256 ·Status: COMPLETED ·Phase: PHASE1
-
Exercise Resistance in Type 2 Diabetes
NCT01911104 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Day-night Rhythm in Muscle Metabolism of Prediabetics
NCT03733743 ·Status: COMPLETED ·Phase: NA
-
Training, Detraining, Retraining and Glycemic Control in Patients With Type 2 Diabetes
NCT01580475 ·Status: COMPLETED ·Phase: NA
-
Exercise Study to Help Patients Who Have Type 2 Diabetes and Depression.
NCT01024790 ·Status: COMPLETED ·Phase: PHASE1
-
HOme-Based Exercise for Patients With Type 2 Diabetes
NCT03103126 ·Status: WITHDRAWN ·Phase: NA
-
Muscle Strength Training for Older Adults With Type II Diabetes
NCT03280758 ·Status: UNKNOWN ·Phase: NA
-
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise
NCT02977442 ·Status: COMPLETED ·Phase: NA
-
Weight Off-loading Training, Cardiovascular Indices, Diabetes
NCT06974422 ·Status: COMPLETED ·Phase: NA
-
Inspiratory Muscle Strength Training in Adults With Type 2 Diabetes
NCT05643768 ·Status: COMPLETED ·Phase: NA
-
Mechanisms of Skeletal Muscle Insulin Resistance in Older Adults
NCT02971098 ·Status: COMPLETED ·Phase: NA
-
Effect of Age on Glucose and Lipid Metabolism
NCT01737164 ·Status: COMPLETED ·Phase: NA
-
The Effects of Supervised Aerobic Training on Dyslipidemia Among Diabetic Older Patients
NCT06246435 ·Status: COMPLETED
-
Exercise and Activity Guidance in Older Adults With Diabetes
NCT00344240 ·Status: COMPLETED ·Phase: NA
-
The Effectiveness of Resistance Training on Glycemic Control for Patients With Type 2 Diabetes in Cardiac Rehabilitation
NCT02707380 ·Status: COMPLETED ·Phase: NA