Comparison of Metformin and Pioglitazone in Regulating Menstrual Irregularities and Hyperandrogenism
NCT03757923 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 110
Last updated 2018-11-29
Summary
To compare metformin with pioglitazone in improving menstrual irregularities and hyperandrogenism in women with PCOS so that an alternate and better treatment option will be available for hyperinsulinemia in pcos patients.
Conditions
- Menstrual Irregularities
- Hyperandrogenism
Interventions
- DRUG
-
TAB METFORMIN
INSULIN SENSITIZING AGENTS
- DRUG
-
TAB PIOGLITAZONE
INSULIN SENSITIZING AGENT
Sponsors & Collaborators
-
Dow University of Health Sciences
lead OTHER
Principal Investigators
-
Bader F Zuberi, FCPS · Dow University of Health Sciences
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-06-18
- Primary Completion
- 2018-12-17
- Completion
- 2019-01-31
Countries
- Pakistan
Study Locations
More Related Trials
-
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
NCT06479434 ·Status: COMPLETED ·Phase: NA
-
Comparison of Myoinositol and Metformin in PCO
NCT04204044 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Effect of Metformin on Patients With Polycystic Ovary Syndrome
NCT05802212 ·Status: COMPLETED ·Phase: NA
-
Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
NCT01021579 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome
NCT04113889 ·Status: COMPLETED ·Phase: PHASE2
-
Ovulation Induction in Clomiphene Citrate Resistant PCO Women
NCT02341703 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS
NCT01909141 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
NCT06576375 ·Status: RECRUITING ·Phase: PHASE3
-
SGLT2 Inhibitors in Patients With PCOS
NCT04700839 ·Status: COMPLETED ·Phase: PHASE4
-
Insulin Sensitizers Role in Control of PCOS Vicious Cycle.
NCT06170463 ·Status: COMPLETED ·Phase: PHASE1
-
Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS
NCT05680805 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity
NCT06140108 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Metformin Treatment of Pregnant Women With Polycystic Ovary Syndrome: a Pilot Study
NCT03259919 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome
NCT00319293 ·Status: UNKNOWN ·Phase: NA
-
Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome
NCT00679679 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF
NCT01438190 ·Status: UNKNOWN ·Phase: PHASE4
-
Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)
NCT01070160 ·Status: COMPLETED
-
Comparing the Effects of Oral Contraceptive Pills Versus Metformin
NCT03229057 ·Status: COMPLETED ·Phase: PHASE3
-
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
NCT02802215 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Metformin and Gestational Diabetes in High-risk Patients: a RCTs
NCT00883259 ·Status: UNKNOWN ·Phase: PHASE4
-
Pioglitazone Treatment in Polycystic Ovary Syndrome
NCT00145340 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Compare Between Combimed Metformin-letrozole and Ovarian Drilling in Pcos With Bilateral Ovarian Drilling in Clomiphene-resistant Infertile Women With Polycystic Ovarian Syndrome
NCT01693289 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial
NCT01573377 ·Status: COMPLETED ·Phase: NA
-
Semaglutide in Women With Polycystic Ovary Syndrome and Obesity
NCT06896981 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Study on the Efficacy and Safety of Chiglitazar Sodium in PCOS With T2DM
NCT05760677 ·Status: UNKNOWN ·Phase: PHASE1