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Effect of Metformin and Probiotics on Gut Microbiome in Healthy Subjects

NCT03756623 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2019-08-21

No results posted yet for this study

Summary

This clinical trial is designed to evaluate the alteration of gut microbiome in healthy subjects after a 12-week metformin and/or probiotics administration.

Conditions

  • Healthy

Interventions

DRUG

Metformin powder

0.5g of Metformin powder administered three times a day orally before meal

DRUG

Probiotics powder

0.5g of Probiotics powder administered three times a day orally before meal

OTHER

Placebo powder

0.5g of Placebo powder administered three times a day orally before meal

Sponsors & Collaborators

  • The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

    lead OTHER

Principal Investigators

  • Mingming Zhang, MD,PhD · Drum Tower hospital affiliated to Nanjing University Medical School

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2019-03-31
Completion
2019-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03756623 on ClinicalTrials.gov