Antibiotic Therapy vs Laparscopic Appendectomy in Pediatric Chronic Appendicitis

Summary

This clinical trial will compare antibiotic therapy with laparoscopic appendectomy in the treatment of pediatric chronic appendicitis in china. Enrolled patients will be randomised and an allocation ratio of 1:1 will be made via weighted minimisation, where half of the patients will receive antibiotic therapy with intravenous Ceftazidime sodium, while the other half will have a laparoscopic appendicectomy.

Conditions

• Chronic Appendicitis

Interventions

DRUG

Ceftazidime

Patients choosing AT group were admitted to the hospital for observation and to receive intravenous antibiotics Intravenous Ceftazidime sodium (50mg/kg/dose every 12 hours) was administered for 3 days.

PROCEDURE

appendectomy

APPT group consisted of admission to the hospital with promptinitiation of intravenous antibiotics and appendectomy

Sponsors & Collaborators

• Zunyi Medical College

  lead OTHER

Principal Investigators

• yuanmei Liu · Zunyi Medical College

• peihong Yan, MD · Children's hospital of guiyang

• Shengli Gu, MD · Zunyi First People's Hospital

• Lei Geng, MD · Affiliated hospital of Binzhou

• Ziyong Li, MD · Children's hospital of Dalian

• Guoqing He, MD · People's Hospital of Anshun City of Guizhou Province

• Xuanzao Wu, MD · Medical university of Guizhou

• Guohong Yang · people hospital of Suiyang

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

3 Years

Max Age

15 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-01-01

Primary Completion

2021-01-01

Completion

2022-01-01

Countries

• China

Study Locations