Yorkshire Enhanced Stop Smoking Study

Summary

Lung cancer rates are higher in Yorkshire than the rest of the UK, and this is due to higher rates of smoking. Deaths from lung cancer can be reduced using regular lung scans (screening) and by helping people stop smoking. As well as detecting cancers, scans can also show evidence of damage to lungs (emphysema) and heart arteries (calcification). This study will test whether people can be encouraged to quit smoking by giving them pictures from their own scans showing possible lung and heart damage, along with information about how stopping smoking reduces their risk of cancer and heart attacks.

Conditions

• Cancer, Lung
• Respiratory Disease
• Heart Diseases

Interventions

OTHER

Intervention

In addition to usual care, personalised feedback from the participants screening appointment will be provided; * For participants with emphysema, an image of their own emphysematous lung compared to a library image of normal lung, or a section of their own non-emphysematous lung. Where emphysema is not present, library pictures showing normal and emphysematous lung will be used. * For participants with coronary artery calcification, a cross sectional segment from their chest scan (either horizontal or vertical) showing the calcium compared to a library image of coronary arteries without calcification and/or a healthy section of the participant's own heart scan. Where coronary artery calcification is not present, library pictures showing normal and calcified coronary arteries will be provided.

OTHER

Usual Care

Smoking cessation support in line with NICE PH48 guidelines

Sponsors & Collaborators

• The Leeds Teaching Hospitals NHS Trust

  collaborator OTHER

• University of Leeds

  collaborator OTHER

• Cardiff University

  collaborator OTHER

• University of Manchester

  collaborator OTHER

• University College, London

  collaborator OTHER

• University of York

  collaborator OTHER

• Yorkshire Cancer Research

  collaborator OTHER

• University of Nottingham

  lead OTHER

Principal Investigators

• Rachael L Murray, BSc MS MSc PhD · University of Nottingham

• Matthew Callister, MA, BM BCh, MEd, FRCP, PhD · The Leeds Teaching Hospitals NHS Trust

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

55 Years

Max Age

80 Years

Sex

MALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-07-01

Primary Completion

2022-03-21

Completion

2022-03-21

Countries

• United Kingdom

Study Locations