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The Effect of MTA and PRF Application in Periapical Lesions

NCT03743987 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2019-02-25

No results posted yet for this study

Summary

A total of 40 periapical lesions from the 33 patient undergoing apical surgery were randomly selected from December 2016-November 2017. Patients were informed about the surgical procedure and signed a consent form. Groups were divided in to 4; as control, MTA (mineral trioxide aggregate), PRF (platelet rich fibrin) and MTA+PRF groups. Apical resection was performed in all groups. No other interventions were made to the control group.

Routine radiographs were taken in the 1st. 3th and 6th months. In the (approximately) 12th month of the procedures computerized tomography scans were taken. Primary healing of the periapical tissues were evaluated and the outcomes were measured. Patients have still been under control for the long term outcomes of the study.

Conditions

  • Apical Periodontitis
  • Wound Heal

Interventions

PROCEDURE

control group

a procedure used to prevent or resolves apical periodontitis.

PROCEDURE

MTA group

a procedure used to prevent or resolves apical periodontitis.

PROCEDURE

PRF group

a procedure that is used for wound healing

PROCEDURE

MTA + PRF group

a procedure used to prevent or resolves apical periodontitis in combination with a procedure that is used for wound healing.

Sponsors & Collaborators

  • Recep Tayyip Erdogan University Training and Research Hospital

    lead OTHER

Principal Investigators

  • Nazife Begüm KARAN, PhD, DDS · Recep Tayyip Erdogan University

  • Banu Arıcıoğlu, PhD, DDS · Recep Tayyip Erdogan University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-12-20
Primary Completion
2018-11-05
Completion
2018-11-05

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03743987 on ClinicalTrials.gov