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Association Between Pseudoexfoliation Syndrome and Diabetes Mellitus

NCT03741153 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2018-11-14

No results posted yet for this study

Summary

Pseudoexfoliation syndrome (PEX) is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye and was first described in 1917 by Lindberg. It is frequently associated with open angle glaucoma, known as pseudoexfoliation glaucoma, which is one of the most common identifiable forms of secondary open angle glaucoma worldwide. Despite extensive research, the exactchemical nature of the fibrillar material is unknown. It is believed to be secreted multifocally in the iris pigment epithelium, the ciliary epithelium, and the peripheral anterior lens epithelium.

Conditions

  • Lens Diseases

Interventions

DEVICE

slit lamp

1. Presence of white grayish exfoliation material on the anterior lens capsule and / or the pupillary margin. 2. Poor pupillary dilatation due to atrophy of the dilator pupillae muscle. 3. The presence of pseudoexfoliative material (PXF)in cilliary processes and zonules. 4. presence of PXF material scattered on corneal endothelium. 5. Flecks of the exfoliative material on the anterior chamber which leads to glaucoma.

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-31
Primary Completion
2020-12-31
Completion
2021-03-14

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03741153 on ClinicalTrials.gov