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Evaluation of the Effects of Platelet Rich Fibrin on the Palatal Mucosal Healing

NCT03734328 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2018-11-09

No results posted yet for this study

Summary

Subepithelial connective tissue graft (SCTG) has greater predictability for root coverage and causes minimal discomfort to patient. Although donor site heals with primary intention causing less scar tissue, in some different harvesting procedures primary flap closure may not be achieved due to nature of thick palatal tissues. Some potential complications may occur at donor site such as: necrosis of graft and palatal site, pain, excessive hemorrhage, protracted discomfort, donor site infection and in some cases donor site paresthesia. Platelet rich fibrin (PRF) is a platelet concentrate obtained by a simple procedure that does not require biochemical blood involvement.Based on the known biological effects of PRF, the aim of this study is to evaluate the PRF in the management of soft tissue donor sites in term of bleeding and pain sensation, and to observe the changes in tissue healing after a subepithelial connective tissue graft procedure at palatal donor site.

Conditions

  • Wound Healing
  • Pain, Postoperative
  • Bleeding Wound

Interventions

PROCEDURE

connective tissue graft

* anesthesia of the palatal mucosa * subepithelial connective tissue graft harvesting * suturing (5/0 silk suture)

PROCEDURE

connective tissue graft&PRF

anesthesia of the palatal mucosa subepithelial connective tissue graft harvesting -suturing (5/0 silk suture)

OTHER

connective tissue graft&PRF

* taking blood from patient * centrifuging blood * obtain PRF

Sponsors & Collaborators

  • Pamukkale University

    lead OTHER

Principal Investigators

  • Murat AKGUL, prof. dr. · Pamukkale University Faculty of Dentistry Department of Periodontolgy

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-06-30
Primary Completion
2018-11-01
Completion
2018-11-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03734328 on ClinicalTrials.gov