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CRT Versus Surgery for Retroperitoneal or Paraaortic Lymph Node Recurrence of CRC

NCT03725254 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 180

Last updated 2019-01-23

No results posted yet for this study

Summary

The study aims to compare the effects of chemoradiation versus radical surgery in treating retro-peritoneal or para-aortic lymph node metastasis in colorectal cancer. By prolonging patients' progression-free survival, local control rate and overall survival, investigators can conclude the best regimen for colorectal cancer patients.

Conditions

  • Colorectal Cancer
  • Retroperitoneal Lymph Node Metastasis
  • Para-aortic Lymph Node Metastasis

Interventions

PROCEDURE

lymphadenectomy

The retroperitoneal lymphadenectomy includes all lymph, fat, and connective tissue in the retroperitoneal space.

RADIATION

chemoradiotherapy

Radiation therapy is highly appropriate, based on the characteristics of the lesion and the surrounding critical organs, and select IMRT or stereotactic radiotherapy (SBRT).

Sponsors & Collaborators

  • Fudan University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-20
Primary Completion
2021-10-01
Completion
2024-10-01

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03725254 on ClinicalTrials.gov