Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement
NCT03716531 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 199
Last updated 2025-12-09
Summary
This research study is studying an intervention as a possible treatment for pancreatic cancer.
Conditions
- Pancreas Cancer
Interventions
- RADIATION
-
IORT
IORT works by delivering radiation therapy to the tumor while reducing the amount of healthy tissue exposed to the radiation therapy
Sponsors & Collaborators
-
IntraOp/Mobetron
collaborator UNKNOWN -
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Jennifer Wo, MD · Massachusetts General Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-03-19
- Primary Completion
- 2025-08-26
- Completion
- 2027-12-31
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma
NCT07126158 ·Status: RECRUITING ·Phase: PHASE2
-
Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer
NCT04975516 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine and Radiation Therapy in Treating Patients With Cancer of the Pancreas
NCT00010166 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Neoadjuvant Short Course IMRT Followed by Surgery and IORT for Resectable Pancreatic Cancer
NCT01372735 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Chemoradiation With Gemcitabine in Combination With Panitumumab for Patients With Locally Advanced Pancreatic Cancer
NCT01175733 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Gemcitabine Plus Radiation Therapy in Treating Patients With Pancreatic Cancer
NCT00003546 ·Status: COMPLETED ·Phase: PHASE2
-
Postoperative Proton Radiotherapy With Chemo for Pancreatic Cancer
NCT01553019 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Low-Dose Fractionated Radiotherapy in Patients With Locally Advanced Metastatic Pancreatic Cancer
NCT00761345 ·Status: COMPLETED ·Phase: PHASE1
-
Nab-Paclitaxel Plus Gemcitabine With Concurrent MR-Guided IMRT in Patients With Locally Advanced Pancreatic Cancer
NCT02283372 ·Status: COMPLETED ·Phase: PHASE1
-
Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
NCT03257033 ·Status: RECRUITING ·Phase: PHASE3
-
Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer
NCT02241551 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Unresectable Pancreatic Cancer
NCT00025168 ·Status: COMPLETED ·Phase: PHASE2
-
Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma
NCT04331041 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Gemcitabine, Herceptin and Radiation to Treat Cancer of the Pancreas
NCT00005926 ·Status: COMPLETED ·Phase: PHASE2
-
Ablative Carbon Ion Radiotherapy With Pencil Beam Scanning for Locally Advanced Unresectable Pancreatic Cancer
NCT05424159 ·Status: RECRUITING ·Phase: NA
-
A Study of Photon and Proton Chemoradiotherapy as Definitive or Neoadjuvant Therapy in Non-Metastatic Pancreatic Cancer
NCT03902600 ·Status: ACTIVE_NOT_RECRUITING
-
Neoadjuvant Stereotactic Body Radiation Therapy for Resectable Adenocarcinoma of the Pancreatic Head and/or Body
NCT02208024 ·Status: COMPLETED ·Phase: NA
-
A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer
NCT02481635 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Dose-Painted Intensity Modulated Radiotherapy Pancreas (DP-IMRT Pancreas)
NCT06024824 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study of Neoadjuvant Treatment in Patients With Pancreatic Cancer That is Potentially Resectable
NCT01531712 ·Status: TERMINATED ·Phase: PHASE2
-
Role of Cyberknife Stereotactic Radiation Therapy (SBRT) Followed by Gemcitabine for Patients With Locally Advanced Pancreatic Cancer
NCT01304160 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Trial of Chemo & Radiation Therapy for Pancreatic Cancer
NCT00424827 ·Status: COMPLETED ·Phase: PHASE2
-
Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
NCT01781728 ·Status: COMPLETED ·Phase: PHASE2
-
Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by Surgery
NCT00599833 ·Status: COMPLETED ·Phase: PHASE2
-
PhI Study of Erbitux & Gemcitabine w/Radiation Therapy for Locally Adv. Pancreas Ca
NCT00467116 ·Status: COMPLETED ·Phase: PHASE1