Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Unresectable Pancreatic Cancer
NCT00025168 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2021-09-09
Summary
RATIONALE: Drugs used in chemotherapy, such as gemcitabine and irinotecan, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy and radiation therapy in treating patients who have locally advanced, unresectable pancreatic cancer.
Conditions
Interventions
- DRUG
-
gemcitabine hydrochloride
- DRUG
-
irinotecan hydrochloride
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Wake Forest University Health Sciences
lead OTHER
Principal Investigators
-
Arthur William Blackstock, MD · Wake Forest University Health Sciences
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-11-01
- Primary Completion
- 2003-08-29
- Completion
- 2003-08-29
Countries
- United States
Study Locations
More Related Trials
-
Gemcitabine Plus Radiation Therapy in Treating Patients With Pancreatic Cancer
NCT00003546 ·Status: COMPLETED ·Phase: PHASE2
-
Pemetrexed, Gemcitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer
NCT00310050 ·Status: TERMINATED ·Phase: PHASE1
-
Gemcitabine With or Without Radiation Therapy in Treating Patients With Pancreatic Cancer
NCT00057876 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial of Chemo & Radiation Therapy for Pancreatic Cancer
NCT00424827 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer
NCT00049348 ·Status: COMPLETED ·Phase: PHASE2
-
High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
NCT01921751 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine, Herceptin and Radiation to Treat Cancer of the Pancreas
NCT00005926 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by Surgery
NCT01032057 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients with Pancreatic Cancer
NCT01821612 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Irinotecan, Gemcitabine and Radiation Therapy for Pancreatic Cancer
NCT00192712 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Combination Chemotherapy Plus Radiation Therapy With or Without Tipifarnib in Treating Patients With Locally Advanced Pancreatic Cancer
NCT00026104 ·Status: COMPLETED ·Phase: PHASE2
-
Conatumumab, Gemcitabine Hydrochloride, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer
NCT01017822 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Panitumumab, Chemotherapy, and External-Beam Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot be Removed by Surgery
NCT00601627 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Radiation Therapy Plus Surgery in Treating Patients With Advanced Cancer of the Pancreas
NCT00020345 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine Plus Radiation Therapy in Treating Patients With Pancreatic Cancer
NCT00003426 ·Status: COMPLETED ·Phase: PHASE1
-
Intensity-Modulated Radiation Therapy and Gemcitabine in Treating Patients With Locally Advanced Pancreatic Cancer
NCT00878657 ·Status: TERMINATED ·Phase: PHASE1
-
Testing the Combination of Two Approved Chemotherapy Drugs and Radiation Prior to Surgery in Localized Pancreatic Cancer
NCT03492671 ·Status: RECRUITING ·Phase: PHASE2
-
Phase II Gemcitabine + Fractionated Stereotactic Radiotherapy for Unresectable Pancreatic Adenocarcinoma
NCT01146054 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Pancreatic Cancer That Cannot Be Removed by Surgery
NCT00004003 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery
NCT01013649 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy and Chemotherapy in Treating Patients With Cancer of the Pancreas or Stomach
NCT00003157 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Gemcitabine and Cyberknife Radiation Therapy for Pancreatic Cancer
NCT01051284 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy Study of Gemcitabine, Paclitaxel, and Irradiation in the Treatment of Pancreatic Cancer
NCT00226746 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Phase I Trial of Gemcitabine and Radiation in Locally Advanced Unresectable Cancer of the Pancreas
NCT00001431 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic Cancer
NCT01851174 ·Status: TERMINATED ·Phase: PHASE2