Measurement of the Partial Pressure of Oxygen in Cutaneous Tumors Using Electron Paramagnetic Resonance (EPR) Oximetry
NCT03716193 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2026-02-27
Summary
This protocol will take measurements of a variety of tumors involving the skin in order to assess changes in tumor oxygen from hyperoxygenation therapy and standard cancer-directed treatments, to demonstrate the clinical feasibility of using in vivo Electron Paramagnetic Resonance (EPR) Oximetry to obtain clinically useful measurements of tumor oxygen levels from cancer patients.
Conditions
- Skin Lesion
- Skin Cancer
- Skin Melanoma
- Tumor Skin
Interventions
- OTHER
-
Oxygen
Patients will be given oxygen via a facemask during the measurement session
Sponsors & Collaborators
-
West Virginia Clinical and Translational Science Institute
collaborator OTHER -
Mary Babb Randolph Cancer Center at West Virginia University Hospitals
collaborator OTHER -
West Virginia University
lead OTHER
Principal Investigators
-
Todd Tenenholz, MD · West Virginia University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-17
- Primary Completion
- 2022-03-31
- Completion
- 2022-03-31
Countries
- United States
Study Locations
More Related Trials
-
Study of Electronic Brachytherapy for Cutaneous Basal Cell Carcinoma
NCT02939027 ·Status: COMPLETED ·Phase: NA
-
Oxford Pleural Embolisation Trial
NCT06651658 ·Status: RECRUITING ·Phase: NA
-
A Study on Radiation Therapy Guided by the Reflectance Confocal Microscopy (RCM)/Optical Coherence Tomography (OCT) Device in People With Basal Cell Carcinoma
NCT05294120 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Electronic Brachytherapy for the Treatment of NMSC
NCT01016899 ·Status: COMPLETED
-
Optical Imaging for Preoperative Delineation of Nonmelanoma Skin Cancers
NCT02666833 ·Status: UNKNOWN
-
Radiotherapy Treatment Planning Comparison Using SBRT-PATHY (Photons) Versus CARBON-PATHY for Unresectable Bulky Tumors
NCT06390657 ·Status: WITHDRAWN
-
Hypofractionated Radiation Therapy to Improve Immunotherapy Response in Non-Small Cell Lung Cancer
NCT03035890 ·Status: COMPLETED ·Phase: NA
-
Multiple Respiration-Correlated Cone Beam Computed Tomography (CT) Scans to Reduce Target Positioning Errors in Radiotherapy Treatment of Thoracic Cancer
NCT00722605 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
SCINTIX [BgRT} Using RMRS in Solid and Soft Tissue Tumors
NCT06634706 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Magnetic Resonance Imaging (MRI) Solely For Liver Stereotactic Body Radiation Therapy (SBRT)
NCT02722395 ·Status: COMPLETED
-
Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer
NCT03422302 ·Status: RECRUITING ·Phase: NA
-
4D CBCT and Intrafractional Imaging for the Determination of the Most Representative 4D Simulation Planning Technique for Lung SBRT Technique Patients
NCT04717804 ·Status: COMPLETED ·Phase: NA
-
Real Time In-Vivo Body Surface Dosimetry for External Beam Radiation Therapy
NCT02407977 ·Status: COMPLETED
-
Comfort Level of Two Abdominal Compression Methods Used to Hold Patients Still While Undergoing Stereotactic Body Radiation Therapy for Lung Tumors
NCT00866086 ·Status: TERMINATED ·Phase: PHASE1
-
MR-informed Stereotactic Radiotherapy for Treatment of Ultracentral Lung Tumours Utilising a Dedicated MR-simulator for Daily Adaptation Followed by CBCT-guided Treatment Delivery
NCT06815289 ·Status: RECRUITING ·Phase: NA
-
Functional Imaging in Lung SBRT
NCT03121300 ·Status: COMPLETED
-
Validation of a Novel Thoracic Neoplasm Radiotherapy Image Guidance Technique: A Pilot Study
NCT00585819 ·Status: WITHDRAWN ·Phase: NA
-
Thermal Signature of Patients Undergoing Radiation Therapy
NCT00508313 ·Status: WITHDRAWN
-
Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer
NCT02379039 ·Status: COMPLETED
-
SkIN hydrAtion Evaluation With TeRAhertz Scanning
NCT05121207 ·Status: COMPLETED ·Phase: NA
-
Ex Vivo Tumor Visualization and Resection Margin Assessment Using Topically Applied Fluorescent Imaging Agents
NCT06292845 ·Status: RECRUITING ·Phase: NA
-
Stereotactic Radiosurgery in Patients With Head and Neck Region Tumours
NCT06472570 ·Status: RECRUITING ·Phase: NA
-
Patient Experience Data in Radiation Oncology
NCT05224297 ·Status: RECRUITING
-
BReath Hold TecHniquEs for Radiotherapy of Esophageal Carcinoma
NCT06317272 ·Status: TERMINATED ·Phase: NA
-
Breath-Hold Technique for Pancreatic Stereotactic Body Radiation Therapy (SBRT) Patients
NCT04843306 ·Status: TERMINATED ·Phase: NA