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Body Composition, Bone Health and Hormonal Status in HIV-1-infected Individuals

NCT03708289 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2018-10-17

No results posted yet for this study

Summary

Improved survival of people living with HIV has resulted in an increased occurrence of other comorbidities, such as cardiovascular, renal, bone and endocrine pathologies.

The data that is currently available on cART-associated changes in bone mineral density, body composition and hormonal values is short-term and mainly derived from patients initiating cART in accordance with previous treatment guidelines. As current guidelines recommend earlier cART initiation and as PI-based regimens are becoming less frequently used, a favorable outcome on bone health, body composition measures and endocrine status might be expected.

This study will therefore prospectively document alterations in bone mineral density, body composition and endocrine status in HIV-infected patients in whom, in the current treatment era, an INSTI-based cART regimen is initiated as a first line regimen.

Conditions

Interventions

RADIATION

DXA scan

total and hip and spine dual energy x-ray absorptiometry

OTHER

Achilles bone US

OTHER

Medical body composition measurements

OTHER

Resting energy expenditure measurement

Sponsors & Collaborators

  • Universitair Ziekenhuis Brussel

    lead OTHER

Principal Investigators

  • Sabine D Allard, PhD · Universitair Ziekenhuis Brussel

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2018-10-31
Completion
2018-10-31

Countries

  • Belgium

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03708289 on ClinicalTrials.gov