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Vascular Implications of a Naturally Occurring Asthma Exacerbation

NCT03679299 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 3

Last updated 2024-07-05

No results posted yet for this study

Summary

Although asthma is a disease of the airways, research is now showing that asthmatics are more likely to develop cardiovascular disease (CVD) compared to non-asthmatics. Vascular dysfunction is seen in people at high risk of CVD and has been linked to inflammation. During an asthma attack, levels of inflammation in the whole body increase, which could potentially explain why asthmatics are at increased risk of CVD. In the proposed study the investigators will examine if asthma attacks lead to increased risk of CVD by evaluating inflammatory levels and vascular function directly following asthma attacks, 2 days and 14 days after discharge. The investigators will compare these results to non-asthmatics. The results from this study will help us understand why asthmatics are at increased risk of CVD.

Conditions

Interventions

OTHER

Observational - No intervention

See outcomes

Sponsors & Collaborators

  • University of Alberta

    lead OTHER

Principal Investigators

  • Michael K Stickland, PhD · Professor, Division of Pulmonary Medicine, Department of Medicine; Director, G.F. MacDonald Centre for Lung Health Covenant Health; Scientific Director, Respiratory Health Strategic Clinical Network, Alberta Health Services

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-10-10
Primary Completion
2024-06-30
Completion
2024-06-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03679299 on ClinicalTrials.gov