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Classical Trigeminal Neuralgia and Sodium Channel Mutations

NCT03656497 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 33

Last updated 2018-09-05

No results posted yet for this study

Summary

The most common cause of trigeminal neuralgia is considered to be a neurovascular contact. However, this etiological factor only seem to be present in half of the patient group. Thus the etiology of the other half is unknown.

Gain-of function genetic mutations in voltage gated sodium channels have been hypothesized as playing a role in the etiology of trigeminal neuralgia but it has yet to be confirmed. In recent years gain-of-function mutations have been identified as a causative factor in other pain-diseases presenting with trigeminal neuralgia phenotypic similarities.

Conditions

  • Trigeminal Neuralgia

Interventions

OTHER

Observational

No intervention is conducted as the study aim is to explore the link between pheno- and genetype of trigeminal neuralgia

Sponsors & Collaborators

  • Maastricht University Medical Center

    collaborator OTHER

  • Danish Headache Center

    lead OTHER

Principal Investigators

  • Lars Bendtsen, ass. prof. · Danish Headache Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-11-01
Primary Completion
2018-08-01
Completion
2018-08-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03656497 on ClinicalTrials.gov